Minute™ Albumin Depletion Reagent for Plasma and Serum (20 ml)

Manual & Protocol | MSDS

Human/animal serum and plasma are the best sources of samples for biomarker identification. However, the presence of albumin in large amounts interferes with many assays and functional proteomic analysis. Serum albumin accounts for 50-70% of the total serum protein that causes loss of resolution for 1D and 2D electrophoresis. Effective removal of albumin using our reagent can increase sensitivity of the assay for many folds. Unlike a resin-based depletion kit (that only deals with microliter amounts of a sample), Minute albumin depletion reagent can handle a few microliters and up to several milliliters of samples. Over 90% of albumin can be removed in less than 5 minutes.

1.  Kumadaki, K., Suzuki, N., Tatematsu, K., Doi, Y., & Tsukamoto, K. (2023). Comparison of Biological Activities of BafA Family Autotransporters within Bartonella Species Derived from Cats and Rodents. Infection and Immunity, e00186-22.

2.  Kim, K. H. (2023). Intranasal delivery of mitochondrial protein humanin rescues cell death and promotes mitochondrial function in Parkinson's disease. Theranostics, 13(10), 3330.

3.  Debande, L., Sabbah, A., Kuhn, L., Ngondo, P., Andre, A. C., Roche, B., ... & Marteyn, B. S. (2023). SPATEs promote the survival of Shigella to the plasma complement system upon hemorrhage and bacteremia. bioRxiv, 2023-11.

4.  Kim, C. Y., Kim, J., Yoon, S., Yi, I. J., Lee, H., Seo, S., ... & Yi, S. S. (2024). Advancing the early detection of canine cognitive dysfunction syndrome with machine learning-enhanced blood-based biomarkers. Frontiers in Veterinary Science, 11, 1390296.