Minute™ Plasma Membrane/Protein Isolation and Cell Fractionation Kit (50 Preps)

Manual & Protocol | Material Safety Data Sheets (MSDS)

The Minute^TM kit represents the next-generation product for plasma membrane (PM) isolation and cell fractionation, offering unsurpassed convenience and consistency by eliminating uncontrollable variations associated with traditional homogenization and density gradient centrifugation, including two-phase partitioning.

How it works: cells/tissues are first sensitized by buffer A before passing through the proprietary filter in a zigzag manner when high-speed centrifugal force is applied, resulting in a cell lysate containing ruptured cell membranes and intact nuclei. As a result, nuclear contamination is virtually eliminated. PM is further separated from the cell lysate (a mixture of crude membranes, intact nuclei, cytosol proteins, and organelles) by subsequent differential and density centrifugation with a regular tabletop microcentrifuge. 5 distinct cell fractions (total membrane, PM, cytosol, nucleus, and organelles) can be obtained. The procedure can be completed in less than 45 minutes.

• How to Choose Membrane Protein Isolation Kits

Figure 1. A. SDS-PAGE profiles of total cell lysate (TC) and isolated plasma membrane proteins (PM) from human and rat cultured cells. Lane 1, Human lung cancer cell A549 total cell lysate; Lane 2, Isolated PM of A549; Lane 3, PM of rat REL-6TN cells; Lane 4, Total cell lysate of rat REL-6TN cells.

B. Western blotting: Proteins in A were transferred to nitrocellulose membrane and probed with anti-Na/K ATPase alpha1, a plasma membrane marker (Upstate, Clone 464.6), and anti-lamin B1, a nuclear envelope marker (ab16048, Abcam Cambridge, MA). The specific protein bands were visualized by a color metric substrate Opti-4CN (Bio-RAD).

C. Densitometry measurement of Na/K ATPase alpha1 signals in B (TC vs. PM). Total cell lysates were extracted by Minute Denaturing Total Protein Extraction Kit (SD-001, Invent Biotechnologies, Eden Prairie, MN).

Figure 2 A. SDS-PAGE profiles of isolated total membrane proteins from mouse tissues (T=Total Cell Lysate, C=Cytosol Fraction, M= Total Membrane Fraction)

B. Proteins shown in A were transferred to a nitrocellulose membrane and probed with rabbit-anti mouse pan-cadherin (ab6529, Abcam, Cambridge, MA), and anti-actin by Western blotting. The specific protein bands were visualized by a color metric substrate Opti-4CN (Bio-RAD). Signals of pan-cadherin (a 130 kDa plasma membrane marker) were significantly enhanced in total membrane protein fractions. Total cell lysates were extracted by Minute™ Denaturing Total Protein Extraction Kit (SD-001, Invent Biotechnologies, Plymouth, MN).

Figure 3. A. SDS-PAGE profiles of total membrane protein fraction (TM) and isolated plasma membrane protein fraction from mouse tissues. 

B. Western blotting of proteins in A were transferred to nitrocellulose membrane and probed with rabbit anti-cadherin (abcam, Cambridge, MA). The specific protein bands were visualized by a color metric substrate Opti-4CN (Bio-RAD). 

C. Densitometry measurement of cadherin signals in B (TM vs. PM).

Kit includes:

1. Kalabus JL, et al. (2013). Viral Attachment Induces Rapid Recruitment of an Innate Immune Sensor (TRIM5α) to the Plasma Membrane. J Innate Immun 5:414-424.
2. Wen D. et al. (2013). Regulation of BK- expression in the distal nephron by aldosterone and urine pH. Am J Physiol Renal Physiol. 305: F463-F476.
3. Yang J. et al (2014). PLCy1-PKCy signaling-mediated Hsp90a plasma membrane translocation facilitates tumor metastasis. Traffic; 15(8): 861-78.
4. Marry E.W. et al (2014). Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles. Thromb Haemost; 111:647-655.
5. Kutluay, S., et al. (2014). Global Changes in the RNA Binding Specificity of HIV-1 Gag Regulate Virion Genesis, Cell (2014), http://dx.doi.org/10.1016/j.cell.2014.09.057.
6. Leung W-H. et al.(2015). PRL-3 Mediates the protein Maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60.The Journal of Immunology.doi:10.4049/jimmunol.1400817.
7. Henry E., et al. (2015). Beyond Glysolysis: GAPDHs are multifunctional enzymes involved in regulation of ROS, autophage, and plant immune responses. PLoS Genet 11(4): e1005199. doi:10.1371/journal. pgen.1005199.
8. Wen D., et al. (2015). Increased epithelial sodium channel activity contributes to hypertension caused by Na+-Hco- cotransporter electrogenic 2 defficiency. Hypertension. 2015;66:00-00. DOI: 10.1161/HYPERTENSIONAHA.115.05394.
9. Yamaguchi T., et al. (2015). Expression of BAF57 in ovarian cancer cells and drug sensitivity.Cancer Sci 106 (2015) 359–366. doi: 10.1111/cas.12612.
10. Wen D. et al. (2015). Deficient acid handling with distal RTA in the NBCe2 knockout mouse. Am J Physiol Renal Physiol (June 24, 2015). doi:10.1152/ajprenal.00163.2015.
11. Kashiwagi Y, Nagoshi T, Yoshino T, Tanaka TD, Ito K, Harada T, et al. (2015) Expression of SGLT1 in Human Hearts and Impairment of Cardiac Glucose Uptake by Phlorizin during Ischemia- Reperfusion Injury in Mice. PLoS ONE 10(6):e0130605. doi:10.1371/journal.pone.0130605.
12. Georgiou D. K., et al. (2015). Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism doi: 10.1074/jbc.M115.643544 jbc.M115.643544.
13. Devarakonda C. V. et al.(2015). Patient-derived heavy chain antibody targets cell surface HSP90 on breast tumors. BMC Cancer 2015, 15:614 doi:10.1186/s12885-015-1608-z
14. Lin Z-J, D.,et al(2015) PBL13 is a serine/threonine protein kinase that negatively regulates Arabidopsis immune responses. Plant Physiology. doi: http://dx.doi.org/10.1104/pp.15.01391
15. Mickle, A. D., Shepherd, A. J., Loo, L., & Mohapatra, D. P. (2015). Induction of Thermal and Mechanical Hypersensitivity by Parathyroid Hormone-related Peptide (PTHrP) Through Upregulation of TRPV1 Function and Trafficking. Pain, 156(9), 1620.
16. Izumi D., et al. (2016). CXCL12/CXCR4 activation by cancer-associated
17. fibroblasts promotes integrin b1 clustering and invasiveness in gastric cancer. Int. J. Cancer: 138, 1207–1219.
18. Sebla B. Kutluay and Paul D. Bieniasz. (2016) Analysis of HIV-1 Gag-RNA Interactions in Cells and Virions by CLIP-seq. Methods in Mol. Biol. 1354, pp 119-131.
19. Mukai H., et al. (2016) PKN3 is the major regulator of angiogenesis and tumor metastasis in mice. Scientific Reports | 6:18979 | DOI: 10.1038/srep18979.
20. Tao JQ et al. (2016). Onset of Inflammation with Ischemia: Implications for Donor Lung Preservation and Transplant Survival. American Journal of Transplantation. doi: 10.1111/ajt.13794.
21. Vazquez-Medina J.P. et al. (2016). The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation vialysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages. The FASEB Journal. doi: 10.1096/fj.201500146R.
22. Lin W. et al.,( 2016). Syndecan-4 negatively regulates antiviral signaling by mediating RIG-I deubiquitination via CYLD. Nature communications, DOI: 10.1038/ncomms11848. http://www.nature.com/naturecommunications.
23. Hernández-Saavedra, Daniel, et al.(2016) "RTP801 Amplifies Nox-4-dependent Oxidative Stress Induced by Cigarette Smoke." American Journal of Respiratory Cell and Molecular Biology.
24. LEE, S. J., PARK, B. N., ROH, J. H., AN, Y. S., HUR, H., & YOON, J. K. (2016). B Enhancing the Therapeutic Efficacy of 2-Deoxyglucose in Breast Cancer Cells Using Cell-cycle Synchronization. Anticancer Research, 36(11), 5975-5980.
25. Choi, K. M., Kim, W., Hong, J. T., & Yoo, H. S. (2017). Dodeca-2 (E), 4 (E)-dienoic acid isobutylamide enhances glucose uptake in 3T3-L1 cells via activation of Akt signaling. Molecular and Cellular Biochemistry, 426:9-15
26. Hisamatsu, Y., Suzuki, N., Masum, A. A., Shibuya, A., Abe, R., Sato, A. & Aoki, S. (2017). Cationic Amphiphilic Tris-Cyclometalated Iridium (III) Complexes Induce Cancer Cell Death via Interaction with Ca2+-Calmodulin Complex. Bioconjugate Chemistry. 28:507-523
27. Sun, X., Tao, L., Yi, L., Ouyang, Y., Xu, N., Li, D., & Zhang, Z. (2017). N-glycans released from glycoproteins using a commercial kit and comprehensively analyzed with a hypothetical database. Journal of Pharmaceutical Analysis.
28. Luo, Y., Duan, H., Qian, Y., Feng, L., Wu, Z., Wang, F., ... & Yan, X. (2017). Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Research, 27(3), 352-372.
29. Zheng, J., Zhao, Y., Lun, Q., Song, Y., Shi, S., Gu, X., ... & Tu, P. (2017). Corydalis edulis Maxim. Promotes Insulin Secretion via the Activation of Protein Kinase Cs (PKCs) in Mice and Pancreatic β Cells. Scientific Reports, 7, 40454.
30. Hoshi, Y., Uchida, Y., Tachikawa, M., Ohtsuki, S., & Terasaki, T. (2017). Actin filament‐associated protein 1 (AFAP‐1) is a key mediator in inflammatory signaling‐induced rapid attenuation of intrinsic P‐gp function in human brain capillary endothelial cells. Journal of Neurochemistry, 141(2):247-262.
31. Xu, N., Hirohama, D., Ishizawa, K., Chang, W. X., Shimosawa, T., Fujita, T. & Shibata, S. (2017). Hypokalemia and Pendrin Induction by Aldosterone. Hypertension, HYPERTENSINAHA-116.
32. Hayashiuchi, M., Kitayama, T., Morita, K. et al. J Anesth (2017) General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice. Journal of Anesthesia, 1-8. doi:10.1007/s00540-017-2350-2.
33. Gong, B., Shen, W., Xiao, W., Meng, Y., Meng, A., & Jia, S. (2017). The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling. eLife, 6.
34. Ueda, K., Nishimoto, M., Hirohama, D., Ayuzawa, N., Kawarazaki, W., Watanabe, A., ... & Fujita, T. (2017). Renal Dysfunction Induced by Kidney-Specific Gene Deletion of Hsd11b2 as a Primary Cause of Salt-Dependent Hypertension. Hypertension, HYPERTENSIONAHA-116.
35. Asano, S., Taniguchi, Y., Yamawaki, Y., Gao, J., Harada, K., Takeuchi, H., ... & Kanematsu, T. (2017). Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling. Scientific Reports, 7.
36. Bugge, M., Bergstrom, B., Eide, O. K., Solli, H., Kjønstad, I. F., Stenvik, J., ... & Nilsen, N. J. (2017). Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Inflammatory Cytokine Production and Promotes Invasiveness. Journal of Biological Chemistry, jbc-M117.
37. Murgueitio, M. S., Ebner, S., Hörtnagl, P., Rakers, C., Bruckner, R., Henneke, P., ... & Santos-Sierra, S. (2017). Enhanced immunostimulatory activity of in silico discovered agonists of Toll-like receptor 2 (TLR2). Biochimica et Biophysica Acta (BBA)-General Subjects.
38. Gu, S., Sachleben, J. R., Boughter, C. T., Nawrocka, W. I., Borowska, M. T., Tarrasch, J. T., ... & Adams, E. J. (2017). Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vγ9Vδ2 T cell activation. Proceedings of the National Academy of Sciences, 201707547.
39. Ferioli, S., Zierler, S., Zaißerer, J., Schredelseker, J., Gudermann, T., & Chubanov, V. (2017). TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg· ATP. Scientific Reports, 7.
40. Sugimoto, R., Watanabe, H., Ikegami, K., Enoki, Y., Imafuku, T., Sakaguchi, Y., ... & Tanaka, M. (2017). Down-regulation of ABCG2, a urate exporter, by parathyroid hormone enhances urate accumulation in secondary hyperparathyroidism. Kidney international, 91(3), 658-670.
41. Lee, A., Choi, K. M., Jung, W. B., Jeong, H., Kim, G. Y., Lee, J. H., ... & Yoo, H. S. (2017). Enhancement of Glucose Uptake by Meso-Dihydroguaiaretic Acid through GLUT4 Up-Regulation in 3T3-L1 Adipocytes. Molecules, 22(9), 1423.
42. Thornton, P., Sevalle, J., Deery, M. J., Fraser, G., Zhou, Y., Ståhl, S., ... & Nicol, L. S. (2017). TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant. EMBO Molecular Medicine, e201707673.
43. Toyoki, D., Shibata, S., Kuribayashi-Okuma, E., Xu, N., Ishizawa, K., Hosoyamada, M., & Uchida, S. (2017). Insulin stimulates uric acid reabsorption via regulating urate transporter 1 and ATP-binding cassette subfamily G member 2. American Journal of Physiology-Renal Physiology, 313(3), F826-F834.
44. Thorwald, M., Rodriguez, R., Lee, A., Martinez, B., Peti-Peterdi, J., Nakano, D., ... & Ortiz, R. M. (2017). Angiotensin receptor blockade improves cardiac mitochondrial activity in response to an acute glucose load in obese insulin resistant rats. Redox Biology.
45. Liu, J., Liu, W., Yang, L., Wu, Q., Zhang, H., Fang, A., ... & Tang, F. (2017). The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding. Cell Stem Cell.
46. Yokoi, K., Hisamatsu, Y., Naito, K. and Aoki, S. (2017), Design, Synthesis, and Anticancer Activities of Cyclometalated Tris(2-phenylpyridine)iridium(III) Complexes with Cationic Peptides at the 4′-Position of the 2-Phenylpyridine Ligand. Eur. J. Inorg. Chem. doi: 10.1002/ejic.201700846
47. Dong, J., Zhou, Q., Wei, Z., Yan, S., Sun, F., & Cai, X. (2017). Protein kinase A mediates scopolamine-induced mTOR activation and an antidepressant response. Journal of Affective Disorders.
48. Liu, H., Xu, X., Han, T., Yan, L., Cheng, L., Qin, Y., & Chen, Z. J. (2017). A novel homozygous mutation in the FSHR gene is causative for primary ovarian insufficiency. Fertility and Sterility.
49. Chapman, K. T., White, M. P., Wang, X., Park, M., Stadler, G. K., Lowe, R. D & Radel, P. A. (2017). U.S. Patent Application No. 15/406,289.
50. Park, B. N., Lee, S. J., Roh, J. H., Lee, K. H., An, Y. S., & Yoon, J. K. (2017). Radiolabeled Anti- Adenosine Triphosphate Synthase Monoclonal Antibody as a Theragnostic Agent Targeting Angiogenesis. Molecular Imaging, 16, 1536012117737399.
51. Tian, Y., Heng, D., Xu, K., Liu, W., Weng, X., Hu, X., & Zhang, C. (2017). cGMP/PKG-I pathway-mediated GLUT1/4 regulation by NO (nitric oxide) in female rat granulosa cells. Endocrinology.
52. Kameyama, N., Munetoshi, A.N.D.O., Ogawa, S. and Okada, K., Kyowa Hakko Kirin Co Ltd, 2017. Antibody which specifically binds to human crth2. U.S. Patent Application 15/342,534.
53. Claffey, Kevin P., Charan Devarakonda, and Daniel Kita. "ANTIBODY AND ANTIGEN-BINDING FRAGMENT COMPOSITIONS TARGETING CELL SURFACE ANTIGENS IN TUMORS AND METHODS OF USE THEREOF." U.S. Patent Application 15/637,402, filed January 4, 2018.
54. Li, C., Du, S., Tian, M., Wang, Y., Bai, J., Tan, P., ... & Li, Y. (2018). The host restriction factor IFITM3 Inhibits Vaccinia Virus Infection. Frontiers in Immunology, 9, 228.
55. Long, L., Pang, X. X., Lei, F., Zhang, J. S., Wang, W., Liao, L. D., ... & Wang, L. D. (2018). SLC52A3 expression is activated by NF-κB p65/Rel-B and serves as a prognostic biomarker in esophageal cancer. Cellular and Molecular Life Sciences, 1-19.
56. Yu, Y., Zhao, Y., Teng, F., Li, J., Guan, Y., Xu, J., ... & Chen, L. Berberine Improves Cognitive Deficiency and Muscular Dysfunction Via Activation of the AMPK/SIRT1/PGC-1A Pathway in Skeletal Muscle from Naturally Aging Rats. The journal of nutrition, health & aging, 1-8.
57. Song, X., Shen, Q., Fan, L., Yu, Q., Jia, X., Sun, Y., ... & Kang, J. (2018). Dehydroepiandrosterone-induced activation of mTORC1 and inhibition of autophagy contribute to skeletal muscle insulin resistance in a mouse model of polycystic ovary syndrome. Oncotarget, 9(15), 11905.
58. Yin, X., Feng, L., Ma, D., Yin, P., Wang, X., Hou, S., ... & Feng, J. (2018). Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone. Journal of Neuroinflammation, 15(1), 97.
59. Zhang, X. L., Ding, H. H., Xu, T., Liu, M., Ma, C., Wu, S. L., ... & Xin, W. J. (2018). Palmitoylation of δ-catenin promotes kinesin-mediated membrane trafficking of Nav1. 6 in sensory neurons to promote neuropathic pain. Sci. Signal., 11(523), eaar4394.
60. Yamauchi, T., Doi, S., Nakashima, A., Doi, T., Sohara, E., Uchida, S., & Masaki, T. (2018). Na+-Cl− cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats. American Journal of Physiology-Renal Physiology.
61. Kameyama, Naoya, A. N. D. O. Munetoshi, Shinya Ogawa, and Kazuki Okada. "Antibody which specifically binds to human CRTH2." U.S. Patent 9,938,349, issued April 10, 2018.
62. Choi, K. M., & Yoo, H. S. (2018). 3, 3′‐Diindolylmethane Enhances Glucose Uptake Through Activation of Insulin Signaling in 3T3‐L1 Adipocytes. Obesity.
63. Liu, Q., Zhao, Y., Zheng, L., Zhu, X., Cui, L., & Cao, Y. (2018). The GPI transamidase complex subunit PbGPI16 of Plasmodium berghei is important for inducing experimental cerebral malaria. Infection and immunity, IAI-00929.
64. Wu, Y., Liu, T., Yuan, Y., & Zhang, Z. (2018). Gene expression profile of TLR7 signaling pathway in the liver of rhesus rotavirus-induced murine biliary atresia. Biochemical and biophysical research communications.
65. Komatsu, W., Kishi, H., Yagasaki, K., & Ohhira, S. (2018). Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species.
66. European Journal of Pharmacology.
67. Uchida, Y., Sumiya, T., Tachikawa, M., Yamakawa, T., Murata, S., Yagi, Y., ... & Couraud, P. O. (2018). Involvement of Claudin-11 in Disruption of Blood-Brain,-Spinal Cord, and-Arachnoid Barriers in Multiple Sclerosis. Molecular Neurobiology, 1-18.
68. Shibata, S., Ishizawa, K., Wang, Q., Xu, N., Fujita, T., Uchida, S., & Lifton, R. P. (2018). ULK1 Phosphorylates and Regulates Mineralocorticoid Receptor. Cell Reports, 24(3), 569-576.
69. Wang, J., Wang, Z., Liu, R., Shuai, L., Wang, X., Luo, J., ... & He, X. (2018). Metabotropic glutamate receptor subtype 2 is a cellular receptor for rabies virus. PLOS Pathogens, 14(7), e1007189.
70. Liu Q, Zhao Y, Zheng L, Zhu X, Cui L, Cao Y. 2018. The glycosylphosphatidylinositol transamidase complex subunit PbGPI16 of Plasmodium berghei is important for inducing experimental cerebral malaria. Infect Immun 86:e00929-17. https://doi.org/10.1128/IAI.00929-17.
71. Liu, D. Y., Chi, T. Y., Ji, X. F., Liu, P., Qi, X. X., Zhu, L., ... & Zou, L. B. (2018). Sigma-1 receptor activation alleviates blood-brain barrier dysfunction in vascular dementia mice. Experimental neurology, 308, 90-99.
72. Kairupan, T. S., Cheng, K. C., Asakawa, A., Amitani, H., Yagi, T., Ataka, K., ... & Inui, A. (2018). Rubiscolin-6 activates opioid receptors to enhance glucose uptake in skeletal muscle. Journal of Food and Drug Analysis7He,
73. X., Du, C., Zou, Y., Long, Y., Huang, C., Chen, F., ... & Zhou, X. (2018). Downregulation of MicroRNA-4463 Attenuates High-Glucose-and Hypoxia-Induced Endothelial Cell Injury by Targeting PNUTS. Cellular Physiology and Biochemistry, 49(5), 2073-2087.
74. Hirohama, D., Ayuzawa, N., Ueda, K., Nishimoto, M., Kawarazaki, W., Watanabe, A., ... & Fujita, T. (2018). Aldosterone Is Essential for Angiotensin II-Induced Upregulation of Pendrin. Journal of the American Society of Nephrology, 29(1), 57-68.
75. Thorwald, M. A. (2018). The Regulation of Cardiac Nrf2 During an Acute Glucose Challenge and the Impact on Mitochondrial Function During Insulin Resistance and Type II Diabetes Mellitus (Doctoral dissertation, UC Merced).
76. Xu et al., (2018) Phosphorylation-Mediated IFN-gR2 MembraneTranslocation Is Required to Activate Macrophage Innate Response. Cell 175, 1–16.
77. Alam, M. B., An, H., Ra, J. S., Lim, J. Y., Lee, S. H., Yoo, C. Y., & Lee, S. H. (2018). Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin-Induced Diabetes. Oxidative Medicine and Cellular Longevity, 2018.
78. Hakuno, D., Kimura, M., Ito, S., Satoh, J., Nakashima, Y., Horie, T., ... & Nishi, H. (2018). Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction. Scientific reports, 8(1), 16749.
79. Wang, D., Ba, H., Li, C., Zhao, Q., & Li, C. (2018). Proteomic Analysis of Plasma Membrane Proteins of Antler Stem Cells Using Label-Free LC–MS/MS. International journal of molecular sciences, 19(11), 3477.
80. Kuroda, H., Tachikawa, M., Yagi, Y., Umetsu, M., Nurdin, A., Miyauchi, E., ... & Terasaki, T. (2018). Cluster of Differentiation 46 is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28). Molecular pharmaceutics.
81. Kataoka, Y., Ohshio, Y., Teramoto, K., Igarashi, T., Asai, T., & Hanaoka, J. Hypoxia‑induced galectin‑3 enhances RhoA function to activate the motility of tumor cells in non‑small cell lung cancer. Oncology Reports.
82. Hoshi, Y., Uchida, Y., Tachikawa, M., Ohtsuki, S., Couraud, P. O., Suzuki, T., & Terasaki, T. (2019). Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood–brain barrier. Journal of Cerebral Blood Flow & Metabolism, 0271678X18822801.
83. Zhang, N., Zhao, H., & Zhang, L. (2019). Fatty acid synthase promotes the palmitoylation of Chikungunya virus nsP1. Journal of virology, 93(3), e01747-18.
84. Nakamura, H., Nagamine, A., Yashima, H., Araki, T., & Yamamoto, K. (2019). Exploration of Proteins Involved in Acquisition of Resistance to Cetuximab. Indonesian Journal of Pharmaceutics, 1(1).
85. Chen, X. Y., Ren, H. H., Wang, D., Chen, Y., Qu, C. J., Pan, Z. H., ... & Li, D. F. (2019). Isoliquiritigenin Induces Mitochondrial Dysfunction and Apoptosis by Inhibiting mitoNEET in a Reactive Oxygen Species-Dependent Manner in A375 Human Melanoma Cells. Oxidative Medicine and Cellular Longevity, 2019.
86. Ishizawa, K., Wang, Q., Li, J., Yamazaki, O., Tamura, Y., Fujigaki, Y., ... & Shibata, S. (2019). Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling. Proceedings of the National Academy of Sciences, 201817281.
87. Nemoto, Y., Kumagai, T., Ishizawa, K., Miura, Y., Shiraishi, T., Morimoto, C., ... & Fujigaki, Y. (2019). Phosphate binding by sucroferric oxyhydroxide ameliorates renal injury in the remnant kidney model. Scientific Reports, 9(1), 1732.
88. i, Y., Yang, T., Yao, Q., Li, S., Fang, E., Li, Y., ... & Li, W. (2019). Metformin prevents colonic barrier dysfunction by inhibiting mast cell activation in maternal separation‐induced IBS‐like rats. Neurogastroenterology & Motility.
89. Peng, W., Tong, C., Li, L., Huang, C., Ran, Y., Chen, X., ... & Luo, X. (2019). Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia. The FASEB Journal, fj-201802058RR.
90. Zhong, W., Xu, M., Li, C., Zhu, B., Cao, X., Li, D., ... & Pan, G. (2019). ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells. Cell Reports, 26(8), 2166-2177.
91. Zhang, S. H., Liu, D. X., Wang, L., Li, Y. H., Wang, Y. H., Zhang, H., ... & Li, B. (2019). A CASPR1–ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells. Journal of Biological Chemistry, jbc-RA118.
92. Nagamine, A., Araki, T., Nagano, D., Miyazaki, M., & Yamamoto, K. L‑Lactate dehydrogenase B may be a predictive marker for sensitivity to anti‑EGFR monoclonal antibodies in colorectal cancer cell lines. Oncology Letters.

93. Essandoh, K., Deng, S., Wang, X., Jiang, M., Mu, X., Peng, J., ... & Fan, G. C. (2019). Tsg101 positively regulates physiologic-like cardiac hypertrophy through FIP3-mediated endosomal recycling of IGF-1R. The FASEB Journal, fj-201802338RR.

94. Ishizawa, K., Wang, Q., Li, J., Xu, N., Nemoto, Y., Morimoto, C., ... & Fujita, T. (2019). Inhibition of Sodium Glucose Cotransporter 2 Attenuates the Dysregulation of Kelch-Like 3 and NaCl Cotransporter in Obese Diabetic Mice. Journal of the American Society of Nephrology, ASN-2018070703.

95. Van Krieken, R., Mehta, N., Wang, T., Zheng, M., Li, R., Gao, B., ... & Austin, R. C. (2019). Cell surface expression of 78 kDa glucose regulated protein (GRP78) mediates diabetic nephropathy. Journal of Biological Chemistry, jbc-RA118.
96. Li, C., Wang, X., Cheng, F., Du, X., Yan, J., Zhai, C., ... & Wang, Q. (2019). Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system. European Journal of Pharmacology.
97. Ni, H. M., Chao, X., Kaseff, J., Deng, F., Wang, S., Shi, Y. H., ... & Jaeschke, H. (2019). Receptor-Interacting Serine/Threonine Kinase 3 (RIP3)–Mixed Lineage Kinase Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers. The American Journal of Pathology.
98. Sheng, J., Shen, L., Sun, L., Zhang, X., Cui, R., & Wang, L. (2019). Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial‐lysosomal crosstalk. Cell Proliferation, e12609.
99. Ghosh, M., Lo, R., Ivic, I., Aguilera, B., Qendro, V., Devarakonda, C., & Shapiro, L. H. (2019). CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration. , 12(579), eaav5938.
100. Liu, W., Wang, X., Wang, S., Ba, X., Xu, T., Wang, X., & Zeng, X. RhoGDI2 positively regulates the Rho GTPases activation in response to the β2 outside‐in signaling in T cells adhesion and migration on ICAM‐1. Journal of Leukocyte Biology.
101. Chang, W., Callan, K. T., & Dragoo, J. L. (2019). The Behavior of Tendon Progenitor Cells from Tendinopathic Tendons: Implications for Treatment. Tissue Engineering, (ja).
102. Wang, D., Zheng, J., Hu, Q., Zhao, C., Chen, Q., Shi, P., ... & Pei, J. (2019). Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis. Cell Death & Differentiation, 1.
103. Yoshii, A., Nagoshi, T., Kashiwagi, Y., Kimura, H., Tanaka, Y., Oi, Y., ... & Yoshimura, M. (2019). Cardiac ischemia–reperfusion injury under insulin-resistant conditions: SGLT1 but not SGLT2 plays a compensatory protective role in diet-induced obesity. Cardiovascular Diabetology, 18(1), 85.
104. Scheiber, I. F., Alarcon, N. O., & Zhao, N. (2019). Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14. Nutrients, 11(7), 1473.
105. Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy. Cell research, 1.
106. Xu, B. Y., Tang, X. D., Chen, J., Wu, H. B., Chen, W. S., & Chen, L. (2019). Rifampicin induces clathrin-dependent endocytosis and ubiquitin–proteasome degradation of MRP2 via oxidative stress-activated PKC-ERK/JNK/p38 and PI3K signaling pathways in HepG2 cells. Acta Pharmacologica Sinica, 1.
107. Xu, Y., Zhou, P., Cheng, S., Lu, Q., Nowak, K., Hopp, A. K., ... & Li, D. (2019). A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy. Cell.
108. Ishii, S., Kitazawa, H., Mori, T., Kirino, A., Nakamura, S., Osaki, N., ... & Tamai, I. (2019). Identification of the Catechin Uptake Transporter Responsible for Intestinal Absorption of Epigallocatechin Gallate in Mice. Scientific Reports, 9(1), 11014.
109. Ljungars, A., Svensson, C., Carlsson, A., Birgersson, E., Tornberg, U. C., Frendéus, B., ... & Mattsson, M. (2019). Deep mining of complex antibody phage pools generated by cell panning enables discovery of rare antibodies binding new targets and epitopes. Frontiers in Pharmacology, 10.
110. Park, B. N., Kim, G. H., Ko, S. A., Shin, G. H., Lee, S. J., An, Y. S., & Yoon, J. K. (2019). Zr-89 Immuno-PET Targeting Ectopic ATP Synthase Enables In-Vivo Imaging of Tumor Angiogenesis. International journal of molecular sciences, 20(16), 3928.
111. Zhang, H., Tian, X., Lu, X., Xu, D., Guo, Y., Dong, Z., ... & Yang, M. (2019). TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation. The Journal of Clinical Investigation, 129(9).
112. Bai, Y., Ma, L. T., Chen, Y. B., Ren, D., Chen, Y. B., Li, Y. Q., ... & Yi, X. N. (2019). Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats. Molecular Brain, 12(1), 1-20.
113. Wu, J., Gao, F., Xu, T., Li, J., Hu, Z., Wang, C., ... & Zhou, B. (2019). CLDN1 induces autophagy to promote proliferation and metastasis of esophageal squamous carcinoma through AMPK/STAT1/ULK1 signaling. Journal of Cellular Physiology.
114. Li, W., Zhang, J., Zou, L., Cui, J., Su, F., Jin, J., ... & Zhao, G. Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants. Oncology Reports.
115. Huang, S., Liu, C., Li, N., Wu, Z., Li, T., Han, D., ... & Wang, J. (2019). Membrane proteomic analysis reveals the intestinal development is deteriorated by intrauterine growth restriction in piglets. Functional & Integrative Genomics, 1-15.
116. Jiang, A. (2019). Identifying Interactions Between Chikungunya Virus And Aedes Aegypti Salivary Gland Proteins.
117. Fujimoto, B. A., Young, M., Carter, L., Pang, A. P., Corley, M. J., Fogelgren, B., & Polgar, N. (2019). The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. American Journal of Physiology-Endocrinology and Metabolism.
118. Takahashi, N., Kimura, A. P., Otsuka, K., Ohmura, K., Naito, S., Yoshida, M., & Ieko, M. (2019). Dreh, a long noncoding RNA repressed by metformin, regulates glucose transport in C2C12 skeletal muscle cells. Life Sciences, 116906.
119. Liu, F., Liu, Q., Yu, C., Zhao, Y., Wu, Y., Min, H., ... & Cao, Y. (2019). An MFS-Domain Protein Pb115 Plays a Critical Role in Gamete Fertilization of the Malaria Parasite Plasmodium berghei. Frontiers in Microbiology, 10.
120. Börtlein, C., Schumacher, F., Kleuser, B., Dölken, L., & Avota, E. (2019). Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis. Frontiers in Cell and Developmental Biology, 7.
121. Mücksch, F., Citir, M., Lüchtenborg, C., Glass, B., Traynor-Kaplan, A., Schultz, C., ... & Kräusslich, H. G. (2019). Quantification of phosphoinositides reveals strong enrichment of PIP 2 in HIV-1 compared to producer cell membranes. Scientific Reports, 9(1), 1-13.
122. Claffey, K. P., Devarakonda, C., & Kita, D. (2019). U.S. Patent Application No. 16/533,937.
123. Wang, C., Wang, J., Shuai, L., Ma, X., Zhang, H., Liu, R., ... & Bu, Z. (2020). The Serine/Threonine Kinase AP2-Associated Kinase 1 Plays an Important Role in Rabies Virus Entry. Viruses, 12(1), 45.
124. Li, L., Zhang, L., Hu, Q., Zhao, L., Nan, Y., Hou, G., ... & Tao, H. (2020). MYH9 Key Amino Acid Residues Identified by the Anti-Idiotypic Antibody to Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 5 Involve in the Virus Internalization by Porcine Alveolar Macrophages. Viruses, 12(1), 40.
125. Fukuyama, K., Fukuzawa, M., Shiroyama, T., & Okada, M. Pathogenesis and pathophysiology of autosomal dominant sleep‐related hypermotor epilepsy with S284L‐mutant α4 subunit of nicotinic ACh receptor. British Journal of Pharmacology.

126. Gong, Y., Wang, C., Jiang, Y., Zhang, S., Feng, S., Fu, Y., & Luo, Y. (2020). Metformin Inhibits Tumor Metastasis through Suppressing Hsp90α Secretion in an AMPKα1-PKCγ Dependent Manner. Cells, 9(1), 144.

127. Zhong, W., Zhao, H., Huang, W., Zhang, M., Zhang, Q., Zhang, Y., ... & Maimaitili, G. (2020). Identification of rare PTCH1 nonsense variant causing orofacial cleft in a Chinese family and an up-to-date genotype-phenotype analysis. Genes & Diseases.

128. Xu, M., Zhu, B., Cao, X., Li, S., Li, D., Zhou, H., ... & Yan, D. (2020). OSBP-Related Protein 5L Maintains Intracellular IP3/Ca2+ Signaling and Proliferation in T Cells by Facilitating PIP2 Hydrolysis. The Journal of Immunology.

129. Sakai, K., Yamazaki, O., Ishizawa, K., Tamura, Y., Wang, Q., Ueno, M., ... & Shibata, S. (2020). Upregulation of renal Na–K–2Cl cotransporter 2 in obese diabetes mellitus via a vasopressin receptor 2-dependent pathway. Biochemical and Biophysical Research Communications.
130. Yuan, J., Zheng, Z., Wang, L., Ran, H., Tang, X., Xie, X., ... & Zhang, J. (2020). The Dynll1-Cox4il Complex Regulates Intracellular Pathogen Clearance via Release of Mitochondrial Reactive Oxygen Species. Infection and Immunity.Fukuyama, K., Okubo, R., Murata, M., Shiroyama, T., & Okada, M. (2020).
131. Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine. Cells, 9(2), 414.Xu, M., Zhu, B., Cao, X., Li, S., Li, D., Zhou, H., ... & Yan, D. (2020). OSBP-Related Protein 5L Maintains Intracellular IP3/Ca2+ Signaling and Proliferation in T Cells by Facilitating PIP2 Hydrolysis. The Journal of Immunology, 204(5), 1134-1145.Xu, M., Zhu, B., Cao, X., Li, S., Li, D., Zhou, H., ... & Yan, D. (2020).
132. Duan, X., Liu, X., Liu, N., Huang, Y., Jin, Z., Zhang, S., ... & Chen, H. (2020). Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation. Cell Death & Disease, 11(2), 1-14
133. Li, S., Shi, B., Huang, K., & Wang, Y. (2020). Different intracellular signalling sensitivity and cell behaviour of porcine insulin with aging. Peptides, 127, 170278.
134. Yang, L., Zhou, G., Li, M., Li, Y., Yang, L., Fu, Q., & Tian, Y. (2020). High Glucose Downregulates Connexin 43 Expression and Its Gap Junction and Hemichannel Function in Osteocyte-like MLO-Y4 Cells Through Activation of the p38MAPK/ERK Signal Pathway. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13, 545.
135. Yoon, J. K., Byeon, H. E., Ko, S. A., Park, B. N., An, Y. S., Lee, H. Y., ... & Lee, S. J. (2020). Cell cycle synchronisation using thiazolidinediones affects cellular glucose metabolism and enhances the therapeutic effect of 2-deoxyglucose in colon cancer. Scientific Reports, 10(1), 1-7.
136. Wang, Q., Wang, Y., Ding, J., Wang, C., Zhou, X., Gao, W., ... & Liu, Z. (2020). A bioorthogonal system reveals antitumour immune function of pyroptosis. Nature, 1-7.
137. Wang, Y., Chen, J., Li, S., Zhang, X., Guo, Z., Hu, J., ... & Yang, G. (2020). Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biology, 101514.
138. Ma, L., Chen, X., Zhao, B., Shi, Y., & Han, F. (2020). Enhanced apoptosis and decreased AMPA receptors are involved in deficit in fear memory in Rin1 knockout rats. Journal of Affective Disorders.
139. Yuan, J., Zheng, Z., Wang, L., Ran, H., Tang, X., Xie, X., ... & Zhang, J. (2020). The Dynll1-Cox4i1 Complex Regulates Intracellular Pathogen Clearance via Release of Mitochondrial Reactive Oxygen Species. Infection and Immunity, 88(4).
140. Fukuyama, K., Fukuzawa, M., Okubo, R., & Okada, M. (2020). Upregulated Connexin 43 Induced by Loss-of-Functional S284L-Mutant α4 Subunit of Nicotinic ACh Receptor Contributes to Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy. Pharmaceuticals, 13(4), 58.
141. Chen, L., Li, X., Wang, H., Hou, P., & He, H. (2020). Annexin A2 gene interacting with viral matrix protein to promote bovine ephemeral fever virus release. Journal of Veterinary Science, 21(2).
142. Zhang, Y., Zhou, P., Wang, Z., Chen, M., Fu, F., & Su, R. (2020). Hsp90β positively regulates μ-opioid receptor function. Life Sciences, 117676.
143. Bogucka, K., Pompaiah, M., Marini, F., Binder, H., Harms, G., Kaulich, M., ... & Grimminger, P. (2020). ERK3/MAPK6 controls IL-8 production and chemotaxis. eLife, 9, e52511.
144. Han, S., Sun, J., Yang, L., & Qi, M. (2020). Role of NDP-and FZD4-Related Novel Mutations Identified in Patients with FEVR in Norrin/β-Catenin Signaling Pathway. BioMed Research International, 2020.
145. Yang, Z., Ma, J., Yang, X., Gao, G., & Zhou, T. (2020). Elevated pigment epithelium-derived factor induces diabetic erectile dysfunction via interruption of the Akt/Hsp90β/eNOS complex.
146. Fukuyama, K., Fukuzawa, M., & Okada, M. (2020). Upregulated and Hyperactivated Thalamic Connexin 43 Plays Important Roles in Pathomechanisms of Cognitive Impairment and Seizure of Autosomal Dominant Sleep-Related Hypermotor Epilepsy with S284L-Mutant α4 Subunit of Nicotinic ACh Receptor. Pharmaceuticals, 13(5), 99.
147. Ding, Y., Zhou, Z., Chen, J., Peng, Y., Wang, H., Qiu, W., ... & Zhang, J. (2020). Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from amino-terminal domain of the GluN1 subunit.
148. Huang, B., Qian, Y., Xie, S., Ye, X., Chen, H., Chen, Z., ... & Héroux, P. (2020). Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y 12 signaling pathway. Cellular & Molecular Immunology, 1-12.
149. Liu, Y. T., Liu, F., Cao, L., Xue, L., Gu, W. T., Zheng, Y. Z., ... & Xie, W. Q. (2020). The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment. Acta Neuropathologica, 1-20.
150. Wang, C., Kawakami-Mori, F., Kang, L., Ayuzawa, N., Ogura, S., Koid, S. S., ... & Chen, X. (2020). Low dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents. Kidney International.
151. Li, Z. Y., Shi, Y. L., Liang, G. X., Yang, J., Zhuang, S. K., Lin, J. B., ... & Zhang, H. T. (2020). Visualization of GLUT1 Trafficking in Live Cancer Cells by the Use of a Dual-Fluorescence Reporter. ACS Omega.
152. Wang, C., Li, Y., Yan, S., Wang, H., Shao, X., Xiao, M., ... & Zhang, N. (2020). Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2. Nature Communications, 11(1), 1-15.
153. Yan, P., Patel, H. J., Sharma, S., Corben, A., Wang, T., Panchal, P., ... & Joshi, S. (2020). Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone. Cell Reports, 31(13), 107840.
154. Zhang, B., Sun, P., Liu, X., Sun, J., Li, D., Liu, Z., ... & Niu, Y. (2020). Role and mechanism of PI3K/AKT/FoxO1/PDX-1 signaling pathway in functional changes of pancreatic islets in rats after severe burns. Life Sciences, 118145.
155. Zhou, Y., Du, B., Kan, M., Chen, S., Tang, B. H., Nie, A. Q., ... & Han, Q. J. (2020). Drug Elimination Alteration in Acute Lymphoblastic Leukemia Mediated by Renal Transporters and Glomerular Filtration. Pharmaceutical Research, 37(8), 1-8.
156. Matamoros, T., Alejo, A., Rodríguez, J. M., Hernáez, B., Guerra, M., Fraile-Ramos, A., & Andrés, G. (2020). African Swine Fever Virus Protein pE199L Mediates Virus Entry by Enabling Membrane Fusion and Core Penetration. mBio, 11(4).
157. Essandoh, K., Deng, S., Wang, X., Li, Y., Li, Q., Mu, X., ... & Fan, G. C. (2020). Tsg101 Is Involved in the Sorting and Re-Distribution of Glucose Transporter-4 to the Sarcolemma Membrane of Cardiac Myocytes. Cells, 9(9), 1936.
158. Chen, Y., Zhao, Z., Li, Y., Li, L., Jiang, Y., Cao, Y., ... & Pang, J. (2020). Characterizations of the Urate Transporter, GLUT9, and Its Potent Inhibitors by Patch-Clamp Technique. SLAS DISCOVERY: Advancing the Science of Drug Discovery, 2472555220949501.
159. Furuhata, R., Kabe, Y., Kanai, A., Sugiura, Y., Tsugawa, H., Sugiyama, E., ... & Tanaka, H. (2020). Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes. Communications Biology, 3(1), 1-13.
160. Wang, Y., Wang, Y., Li, F., Zhang, X., Li, H., Yang, G., ... & Wei, C. (2020). Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System. Cardiovascular Drugs and Therapy, 1-13.
161. Koponen, A., Pan, G., Kivelä, A. M., Ralko, A., Taskinen, J. H., Arora, A., ... & Cho, W. ORP2, a cholesterol transporter, regulates angiogenic signaling in endothelial cells. The FASEB Journal.
162. Talwar, D., Messens, J., & Dick, T. P. (2020). A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex. Nature Communications, 11(1), 1-11.
163. Shiheido-Watanabe, Y., Maejima, Y., Nakagama, S., Tamura, N., Kasama, T., & Sasano, T. (2020). Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor, ameliorates experimental autoimmune myocarditis by suppressing cathepsin-G activity.
     
164. Hendrix, R. D., Ou, Y., Davis, J. E., Odle, A. K., Groves, T. R., Allen, A. R., ... & Barger, S. W. (2020). Alzheimer amyloid β-peptide disrupts membrane localization of glucose transporter 1 in astrocytes: Implications for glucose levels in brain and blood. Neurobiology of Aging.
165. Li, C., Wang, X., Yan, J., Cheng, F., Ma, X., Chen, C., ... & Wang, Q. (2020). Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway. Oxidative Medicine and Cellular Longevity, 2020.
166. Su, R., Zhang, Y., Zhou, P., Gong, Z., & Lu, F. (2020). ABIN-1 in the brain alleviates opioid tolerance by interacting with β-arrestin2 and MOR. Authorea Preprints.
167. Wang, Q., Ishizawa, K., Li, J., Fujii, W., Nemoto, Y., Yamazaki, O., ... & Segawa, H. (2020). Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model. Communications Biology, 3(1), 1-12.
168. Wu, C., Shi, B., Yang, D., Zhang, K., Li, J., Wang, J., ... & Nan, Y. (2020). Porcine Reproductive and Respiratory Syndrome Virus Promotes SLA-DR-Mediated Antigen Presentation of Nonstructural Proteins To Evoke a Nonneutralizing Antibody Response In Vivo. Journal of Virology, 94(21).
169. Fukuyama, K., & Okada, M. (2020). Age-Dependent and Sleep/Seizure-Induced Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy. International Journal of Molecular Sciences, 21(21), 8142.
170. Imai, M., Kawakami, F., Kubo, M., Kanzaki, M., Maruyama, H., Kawashima, R., ... & Ichikawa, T. (2020). LRRK2 Inhibition Ameliorates Dexamethasone-Induced Glucose Intolerance via Prevents Impairment in GLUT4 Membrane Translocation in Adipocytes. Biological and Pharmaceutical Bulletin, 43(11), 1660-1668.
171. Chen, L., Li, X., Wang, H., Hou, P., & He, H. (2020). Annexin A2 gene interacting with viral matrix protein to promote bovine ephemeral fever virus release. Journal of Veterinary Science, 21(2).
172. Thapa, N., Chen, M., Horn, H. T., Choi, S., Wen, T., & Anderson, R. A. (2020). Phosphatidylinositol-3-OH kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4. Nature Cell Biology, 22(11), 1357-1370.
173. Song, G., Li, L., & Yang, Y. (2020). MicroRNA‑329‑3p alleviates high glucose‑induced endothelial cell injury via inhibition of the TLR4/TRAF6/NF‑κB signaling pathway. Experimental and Therapeutic Medicine, 21(1), 1-1.
174. Wang, Y., Zhang, X., Wang, T., Liu, W., Wang, L., Hao, L., ... & Xiao, R. (2020). 27-Hydroxycholesterol promotes the transfer of astrocyte-derived cholesterol to neurons in co-cultured SH-SY5Y cells and C6 cells. Frontiers in Cell and Developmental Biology, 8.
175. Zhao, Z. A., Jiang, Y., Li, L., Chen, Y., Li, Y., Lan, Q., ... & Zhou, P. (2020). Structural Insights into the Atomistic Mechanisms of Uric Acid Recognition and Translocation of Human Urate Anion Transporter 1. ACS Omega.
176. Zhang, Y., Yan, L. S., Ding, Y., Cheng, B. C. Y., Luo, G., Kong, J., ... & Zhang, S. F. (2020). Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes. Frontiers in pharmacology, 10, 1666.
177. Zhang, H. T., Zeng, Q., Wu, B., Lu, J., Tong, K. L., Lin, J., ... & Gao, X. TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy. Cell Death & Disease, 12(1), 1-14.
178. Yano, K., Todokoro, I., Kamioka, H., Tomono, T., & Ogihara, T. (2020). Functional alterations of multidrug resistance-associated proteins 2 and 5, and breast cancer resistance protein upon Snail-induced epithelial–mesenchymal transition in HCC827 cells. Biological and Pharmaceutical Bulletin, 44(1), 103-111.
179. Eustaquio Do Imperio, G., Lye, P., Bloise, E., & Matthews, S. G. (2021). Function of Multidrug Resistance Transporters is Disrupted by Infection Mimics in Human Brain Endothelial Cells. Tissue Barriers, 1860616.
180. Luo, X., Gong, H. B., Gao, H. Y., Wu, Y. P., Sun, W. Y., Li, Z. Q., ... & He, R. R. Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2. Cell Death & Differentiation, 1-19.
181. Zhang, X. L., Lai, R. C., Chen, Z. H., Zhong, X. X., Cao, X. Y., Zhang, X., ... & Xie, M. X. (2021). Foxo1 selectively regulates static mechanical pain by interacting with Nav1. 7. Pain, 162(2), 490-502.
182. Okada, M., Matsumoto, R., Yamamoto, Y., & Fukuyama, K. (2021). Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor. International Journal of Molecular Sciences, 22(3), 1351.
183. Zhang, X., Xu, X., Zhang, Z., Xue, C., Kong, Z., Wu, S., ... & Qin, X. (2021). Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma. International Journal of Biological Sciences, 17(3), 768-780.
184. Mukhopadhyay, S., Biancur, D. E., Parker, S. J., Yamamoto, K., Banh, R. S., Paulo, J. A., ... & Kimmelman, A. C. (2021). Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11. Proceedings of the National Academy of Sciences, 118(6).
185. Elzi, D. J., Bauta, W. E., Sanchez, J. R., Das, T., Mogare, S., Fatland, P. Z., ... & Rebel, V. I. (2021). Identification of a novel mechanism for meso‐tetra (4‐carboxyphenyl) porphyrin (TCPP) uptake in cancer cells. The FASEB Journal, 35(3), e21427.
186. Bai, H., Zhou, R., Barravecchia, M., Norman, R., Friedman, A. E., Yu, D., ... & Dean, D. A.(2021). MRCKα interacts with and mediates Na+, K+-ATPase-induced tight junction assembly in the lung epithelium. JCI insight.
     
187. Xie, M. X., Cao, X. Y., Zeng, W. A., Lai, R. C., Guo, L., Wang, J. C., ... & Zhang, X. L. (2021). ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking. Nature Communications, 12(1), 1-18.
188. Okada, M., Fukuyama, K., Shiroyama, T., & Ueda, Y. (2021). Brivaracetam prevents astroglial l-glutamate release associated with hemichannel through modulation of synaptic vesicle protein. Biomedicine & Pharmacotherapy, 138, 111462.
189. Taniguchi, T., Omura, K., Motoki, K., Sakai, M., Chikamatsu, N., Ashizawa, N., ... & Iwanaga, T. (2021). Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2. Scientific Reports, 11(1), 1-10.
190. Bai, L., Wang, Y., Huo, J., Li, S., Wen, Y., Liu, Q., ... & Li, R. (2021). Simvastatin accelerated motoneurons death in SOD1 G93A mice through inhibiting Rab7-mediated maturation of late autophagic vacuoles. Cell Death & Disease, 12(4), 1-17.
191. Fukuyama, K., Nakano, T., Shiroyama, T., & Okada, M. (2021). Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions. International Journal of Molecular Sciences, 22(8), 4122.
192. Yano, K., Kimura, M., Watanabe, Y., & Ogihara, T. (2021). Rapid Increase of Gastrointestinal P-Glycoprotein Functional Activity in Response to Etoposide Stimulation. Biological and Pharmaceutical Bulletin, 44(5), 701-706.
193. Xiu, M., Huan, X., Ou, Y., Ying, S., & Wang, J. (2021). The basic route of nuclear‐targeted transport of IGF‐1/IGF‐1R and potential biological functions in intestinal epithelial cells. Cell Proliferation, e13030.
194. Xu, J., Wu, S., Wang, J., Wang, J., Yan, Y., Zhu, M., ... & Liu, T. (2021). Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons. Journal of Neuroinflammation, 18(1), 1-17.
195. Malek, M., Wawrzyniak, A. M., Koch, P., Lüchtenborg, C., Hessenberger, M., Sachsenheimer, T., ... & Haucke, V. (2021). Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites. Nature Communications, 12(1), 1-16.
196. Dong, X., Li, Y., Li, W., Kang, W., Tang, R., Wu, W., ... & Zhou, L. (2021). The function of Cav-1 in MDA-MB-231 breast cancer cell migration and invasion induced by ectopic ATP5B. Medical Oncology, 38(6), 1-11.
197. Shen, D., Zhou, C., Cao, M., Cai, W., Yin, H., Jiang, L., & Zhang, S. (2021). Differential Membrane Protein Profile in Bovine X-and Y-Sperm. Journal of Proteome Research.
198. Zhang, X. L., Zhang, J. J., Chen, Z. H., Yang, K. B., Zhang, X., Xiao, Y. B., ... & Xie, M. X. (2021). Difference of pain vulnerability in adult and juvenile rodents: the role of SIRT1-mediated ClC-3 trafficking in sensory neurons. Pain, 162(6), 1882-1896.
199. Zhou, Y., Nie, A. Q., Chen, S., Wang, M. M., Yin, R., Tang, B. H., ... & Zhao, W. (2021). Downregulation of Renal MRPs Transporters in Acute Lymphoblastic Leukemia Mediated by the IL-6/STAT3/PXR Signaling Pathway. Journal of Inflammation Research, 14, 2239-2252.
200. Fukuyama, K., & Okada, M. (2021). Effects of Atypical Antipsychotics, Clozapine, Quetiapine and Brexpiprazole on Astroglial Transmission Associated with Connexin43. International Journal of Molecular Sciences, 22(11), 5623.
201. Ma, K., Qi, G., Wang, B., Yu, T., Zhang, Y., Li, H., ... & Jin, Y. (2021). Ultrasound-activated Au/ZnO-based Trojan nanogenerators for combined targeted electro-stimulation and enhanced catalytic therapy of tumor. Nano Energy, 106208.
202. Fu, Y., Wang, H., Dai, H., Zhu, Q., Cui, C. P., Sun, X., ... & Zhang, L. (2021). OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin. Molecular Cell.
203. Xing, Y. J., Liu, B. H., Wan, S. J., Cheng, Y., Zhou, S. M., Sun, Y., ... & Kong, X. (2021). A SGLT2 Inhibitor Dapagliflozin Alleviates Diabetic Cardiomyopathy by Suppressing High Glucose-Induced Oxidative Stress in vivo and in vitro. Frontiers in Pharmacology, 12, 1756.
204. Notas, G., Panagiotopoulos, A., Vamvoukaki, R., Kalyvianaki, K., Kiagiadaki, F., Deli, A., ... & Castanas, E. (2021). ERα36–GPER1 Collaboration Inhibits TLR4/NFκB-Induced Pro-Inflammatory Activity in Breast Cancer Cells. International Journal of Molecular Sciences, 22(14), 7603.
205. Heidasch, R., Avci, D., Lüchtenborg, C., Kale, D., Beard, H., Mentrup, T., ... & Lemberg, M. K. (2021). Intramembrane protease SPP defines a cholesterol-regulated switch of the mevalonate pathway. bioRxiv.
206. Li, Y., Sun, X. L., Ma, C. L., Li, C., Zhan, Y., Li, W. T., ... & Wang, Y. H. (2021). STX2 Promotes Trophoblast Growth, Migration, and Invasion Through Activation of the PI3K-AKT Pathway in Preeclampsia. Frontiers in Cell and Developmental Biology, 9.
207. Ochiai-Homma, F., Kuribayashi-Okuma, E., Tsurutani, Y., Ishizawa, K., Fujii, W., Odajima, K., ... & Shibata, S. (2021). Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism. Hypertension Research, 1-11.
208. Li, H., Cao, W., Zhang, X. B., Zhang, X. X., Gu, C., Gu, L. M., ... & Lu, M. (2021). Atractylenolide‑1 alleviates gastroparesis in diabetic rats by activating the stem cell factor/c‑kit signaling pathway. Molecular Medicine Reports, 24(4), 1-10.
209. Li, Y., Tang, W., Kang, L., Kong, S., Dong, Z., Zhao, D., ... & Yu, S. (2021). Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms. The Journal of Headache and Pain, 22(1), 1-12.

210. Xingyi Xu; Rongyuan Zhang; Xianfeng Yang; Yao Lu; Zhongmin Yang; et al（2021）<span "="">A Honeycomb‐Like Bismuth/Manganese Oxide Nanoparticle with Mutual Reinforcement of Internal and External Response for Triple‐Negative Breast Cancer Targeted Therapy.<span "="">Advanced Healthcare Materials.

211. Hayashi, S., & Kakikawa, M. (2021). Exposure to 60 Hz magnetic field can affect membrane proteins and membrane potential in human cancer cells. Electromagnetic Biology and Medicine, 1-8.
212. Osada, M., Maruyama, K., Kokame, K., Denda, R., Yamazaki, K., Kunieda, H., ... & Kikuchi, T. (2021). A novel homozygous variant of the thrombomodulin gene causes a hereditary bleeding disorder. Blood Advances.
213. Zhang, Y., Zhou, P., Lu, F., Su, R., & Gong, Z. (2021). ABIN-1 in the brain alleviated opioid tolerance through its action on β-arrestin2. Molecular Pharmacology.
214. Lin, J et al (2021). Hepatokine Pregnancy Zone Protein Governs the Diet-Induced Thermogenesis Through Activating Brown Adipose Tissue Advanced Science.
215. Shimizu-Albergine, M., Basu, D., Kanter, J. E., Kramer, F., Kothari, V., Barnhart, S., ... & Bornfeldt, K. E. (2021). CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins. The Journal of Clinical Investigation.
216. Li, Q., Lu, B., Yang, J., Li, C., Li, Y., Chen, H., ... & Xia, W. (2021). Molecular Characterization of an Aquaporin− 2 Mutation Causing Nephrogenic Diabetes Insipidus. Frontiers in Endocrinology, 12.
217. Shiroyama, T., Fukuyama, K., & Okada, M. (2021). Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43. International Journal of Molecular Sciences, 22(18), 10013.
218. Hou, Y., Li, J., Ding, Y., Cui, Y., & Nie, H. (2021). Luteolin attenuates lipopolysaccharide-induced acute lung injury/acute respiratory distress syndrome by activating alveolar epithelial sodium channels via cGMP/PI3K pathway. Journal of Ethnopharmacology, 114654.
     
219. Zhao, M. M., Lu, J., Li, S., Wang, H., Cao, X., Li, Q., ... & Yang, J. K. (2021). Berberine is an insulin secretagogue targeting the KCNH6 potassium channel. Nature Communications, 12(1), 1-14.
220. Liu, D., Yang, L., Liu, P., Ji, X., Qi, X., Wang, Z., ... & Zou, L. (2021). Sigma–1 receptor activation alleviates blood–brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF–GFRα1–RET pathway. Experimental Neurology, 113867.
221. Gad, S. A., Sugiyama, M., Tsuge, M., Wakae, K., Fukano, K., Oshima, M., ... & Aly, H. H. (2021). The kinesin KIF4 mediates HBV/HDV entry through regulation of surface NTCP localization and can be targeted by RXR agonists in vitro. bioRxiv.
222. Niu, M., Xu, J., Liu, Y., Li, Y., He, T., Ding, L., ... & Xiao, Z. X. J. (2021). FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth. Nature Communications, 12(1), 1-15.
223. Müller, G. A., Tschöp, M. H., & Müller, T. D. (2021). Chip-Based Sensing of the Intercellular Transfer of Cell Surface Proteins: Regulation by the Metabolic State. Biomedicines, 9(10), 1452.
224. Chen, D., Zheng, Q., Sun, L., Ji, M., Li, Y., Deng, H., & Zhang, H. (2021). ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress. Developmental Cell.
225. . Kang, K., Zhang, M., Yue, L., Chen, W., Dai, Y., Lin, K., ... & Zhang, W. (2021). Oxalic acid binds to gustatory receptor Gr23a and inhibits feeding in the brown planthopper. bioRxiv.
226. Rodriguez, R., Lee, A. Y., Godoy-Lugo, J. A., Martinez, B., Ohsaki, H., Nakano, D., ... & Ortiz, R. M. (2021). Chronic AT1 blockade improves hyperglycemia by decreasing adipocyte inflammation and decreasing hepatic PCK1 and G6PC1 expression in obese rats. American Journal of Physiology-Endocrinology and Metabolism.
227. Wang, T. Z., Zuo, G. W., Yao, L., Yuan, C. L., Li, H. F., Lai, Y., ... & Wang, J. W. (2021). Ursolic acid ameliorates adipose tissue insulin resistance in aged rats via activating the Akt‑glucose transporter 4 signaling pathway and inhibiting inflammation. Experimental and Therapeutic Medicine, 22(6), 1-9.
228. Bianchi-Smiraglia, A., Wolff, D. W., Marston, D. J., Deng, Z., Han, Z., Moparthy, S., ... & Nikiforov, M. A. (2021). Regulation of local GTP availability controls RAC1 activity and cell invasion. Nature communications, 12(1), 1-15.
229. Guo, H., Liu, Y., Gu, J., Luo, J., Ma, Y., & Xiao, F. (2021). GJB1 mutations c. 212T> G and c. 311A> C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1. Biochemical and Biophysical Research Communications.
230. Muthusamy, S., Jan, H. M., Hsieh, M. Y., Mondal, S., Liu, W. C., Ko, Y. A., ... & Lin, C. H. (2021). Enhanced enzymatic production of cholesteryl 6ʹ-acylglucoside impairs lysosomal degradation for the intracellular survival of Helicobacter pylori. Journal of Biomedical Science, 28(1), 1-20.
231. Hayata-Takano, A., Shintani, Y., Moriguchi, K., Encho, N., Kitagawa, K., Nakazawa, T., & Hashimoto, H. (2021). PACAP–PAC1 Signaling Regulates Serotonin 2A Receptor Internalization. Frontiers in Endocrinology, 1331.
232. Fukuyama, K., & Okada, M. (2021). Effects of an Atypical Antipsychotic, Zotepine, on Astroglial L-Glutamate Release through Hemichannels: Exploring the Mechanism of Mood-Stabilising Antipsychotic Actions and Antipsychotic-Induced Convulsion. Pharmaceuticals, 14(11), 1116.
233. Yang, B., Jiang, Q., He, S., Li, T., Ou, X., Chen, T., ... & Tan, X. (2021). Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-1. Journal of Molecular and Cellular Cardiology.
234. Wang, J., Liu, B., He, Y., Li, Z., Zhao, Q., Nan, Y., & Wu, C. (2021). Porcine epidemic diarrhea Virus envelope protein blocks SLA-DR expression in barrow-derived dendritic cells by inhibiting promoters activation. Frontiers in Immunology, 4748.
235. Zhang, L., Yu, X., Wu, Y., Fu, H., Xu, P., Zheng, Y., ... & Baker, P. N. (2021). Gestational Diabetes Mellitus-Associated Hyperglycemia Impairs Glucose Transporter 3 Trafficking in Trophoblasts Through the Downregulation of AMP-Activated Protein Kinase. Frontiers in cell and developmental biology, 9.
236. Zhang, N., Zhu, H., Li, Z., & Dong, E. (2021). A novel β2-AR agonist, Higenamine, induces β-arrestin-biased signaling. Science China Life Sciences, 1-12.
237. Song, Y., Huang, H., Hu, Y., Zhang, J., Li, F., Yin, X., ... & Chen, H. (2021). A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis. PLoS pathogens, 17(12), e1010141.
238. Ying, L., Wang, L., Guo, K., Hou, Y., Li, N., Wang, S., ... & Huang, Z. (2021). Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects. Nature Communications, 12(1), 1-14.
239. Zhang, M., Yang, H., Yang, E., Li, J., & Dong, L. (2022). Berberine Decreases Intestinal GLUT2 Translocation and Reduces Intestinal Glucose Absorption in Mice. International Journal of Molecular Sciences, 23(1), 327.
240. Hosoya, T., Uchida, S., Shibata, S., Tomioka, N. H., Matsumoto, K., & Hosoyamada, M. (2022). Xanthine Oxidoreductase Inhibitors Suppress the Onset of Exercise-induced AKI in High HPRT Activity Urat1-Uox Double Knockout Mice. Journal of the American Society of Nephrology.
241. Chen, Y., Wu, X., Zhang, J., Pan, G., Wang, X., Guo, X., ... & Jiang, F. Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance. EMBO reports, e53373.
242. Chen, H., McKeen, T., Chao, X., Chen, A., Deng, F., Jaeschke, H., ... & Ni, H. M. (2022). The role of MLKL in Hepatic Ischemia-Reperfusion Injury of Alcoholic Steatotic Livers. International Journal of Biological Sciences, 18(3), 1096-1106.
243. Wang, J., Luo, J., Wen, Z., Wang, X., Shuai, L., Zhong, G., ... & Bu, Z. (2022). Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor. mBio, 13(1), e02443-21.

244.  Xu, Y., Cheng, S., Zeng, H., Zhou, P., Ma, Y., Li, L., ... & Ding, J. (2022). ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy. Nature Structural & Molecular Biology, 29(1), 67-77.

245. Zhang, H., Liang, A., & Pan, X. (2022). Preparation and Functional Identification of a Novel Conotoxin QcMNCL-XIII0. 1 from Conus quercinus. Toxins, 14(2), 99.

246. Huang, F., Tang, X., Ye, B., Wu, S., & Ding, K. (2022). PSL-LCCL: a resource for subcellular protein localization in liver cancer cell line SK_HEP1. Database, 2022.

247. Son, Y., Choi, C., Saha, A., Park, J. H., Im, H., Cho, Y. K., ... & Lee, Y. H. (2022). REEP6 knockout leads to defective β-adrenergic signaling in adipocytes and promotes obesity-related metabolic dysfunction. Metabolism, 155159.
248. Tennakoon, N., Ryu, J., Ujike, M., Taguchi, F., & Shin, H. J. (2022). Reduction of Cell Fusion by Deletion in the Hypervariable Region of the Spike Protein of Mouse Hepatitis Virus. Viruses, 14(2), 398.
249. Choi, K. J., Lee, J. H., Park, S. B., Na, Y. J., Jung, W. H., Lee, H., & Kim, K. Y. (2022). Development of in vitro three-dimensional drug screening system for obesity-related metabolic syndrome. Journal of Pharmacological Sciences.
250. Wang, X., Luo, J., Wen, Z., Shuai, L., Wang, C., Zhong, G., ... & Bu, Z. (2022). Diltiazem inhibits SARS-CoV-2 cell attachment and internalization and decreases the viral infection in mouse lung. PLoS pathogens, 18(2), e1010343.
251. Shen, H., Xu, X., Fu, Z., Xu, C., & Wang, Y. (2022). The interactions of CAP and LYN with the insulin signaling transducer CBL play an important role in polycystic ovary syndrome. Metabolism, 155164.
252. Fukuyama, K., Motomura, E., Shiroyama, T., & Okada, M. (2022). Impact of 5-HT7 receptor inverse agonism of lurasidone on monoaminergic tripartite synaptic transmission and pathophysiology of lower risk of weight gain. Biomedicine & Pharmacotherapy, 148, 112750.
253. Shen, Q., Wu, X., Zhang, Z., Zhang, D., Yang, S., & Xing, D. Gamma frequency light flicker regulates amyloid precursor protein trafficking for reducing β‐amyloid load in Alzheimer's disease model. Aging Cell, e13573.
254. . Cheng, Y., Kang, X. Z., Cheng, T., Ye, Z. W., Tipoe, G. L., Yu, C. H., ... & Jin, D. Y. (2022). FACI Is a Novel CREB-H–Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity. Cellular and Molecular Gastroenterology and Hepatology.
255. Zeng, C., Xia, T., Zheng, S., Liang, L., & Chen, Y. (2022). Synergistic Effect of Uroguanylin and D1 Dopamine Receptors on Sodium Excretion in Hypertension. Journal of the American Heart Association, e022827.
256. Fukuyama, K., & Okada, M. (2022). High frequency oscillations play important roles in development of epileptogenesis/ictogenesis via activation of astroglial signallings. Biomedicine & Pharmacotherapy, 149, 112846.
257. Bhattacharya, I., Yadavalli, T., Wu, D., & Shukla, D. (2022). Plasma Membrane-Derived Liposomes Exhibit Robust Antiviral Activity against HSV-1. Viruses, 14(4), 799.
258. Li, Y., Wei, J. Y., Liu, H., Wang, K. J., Jin, S. N., Su, Z. K., ... & Chen, Y. H. (2022). An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity. Cell Reports, 39(2), 110656.
259. Ho, J. C., Mir, S. A., Cavalera, M., Esmaeili, P., Tran, T. H., Yann, Z. C., ... & Svanborg, C. (2022). Lipid bilayer composition as a determinant of cancer cell sensitivity to tumoricidal protein‐lipid complexes. BioFactors.
260.  of ROS/Chloride Efflux-Mediated NLRP3 Inflammasome Activation Contributes to Alleviation of Diabetic Cardiomyopathy in Rats after Sleeve Gastrectomy. Oxidative Medicine and Cellular Longevity, 2022.
     
261. Fukuyama, K., & Okada, M. (2022). Brivaracetam and Levetiracetam Suppress Astroglial L-Glutamate Release through Hemichannel via Inhibition of Synaptic Vesicle Protein. International Journal of Molecular Sciences, 23(9), 4473.
262. Alam, M. B., Ra, J. S., Lim, J. Y., Song, B. R., Javed, A., & Lee, S. H. Lariciresinol displays anti‐diabetic activity through inhibition of α‐glucosidase and activation and enhancement of insulin signaling. Molecular Nutrition & Food Research, 2100751.
263. Tabler, C. O., Wegman, S. J., Chen, J., Shroff, H., Alhusaini, N., & Tilton, J. C. (2022). The HIV-1 Viral Protease Is Activated during Assembly and Budding Prior to Particle Release. Journal of Virology, e02198-21.
264. Wang, H., Dai, Y., Clark, N., Boeglin, L., Woo, C., Wooster, R., ... & Sullivan, J. C. (2022). Targeted quantitation of CFTR protein expression in vivo using immunoprecipitation & parallel reaction monitoring tandem mass spectrometry. Translational Medicine Communications, 7(1), 1-11.
265. . Yoo, A., Joo, Y., Cheon, Y., Lee, S. J., & Lee, S. (2022). Neuronal growth regulator 1 promotes adipocyte lipid trafficking via interaction with CD36. Journal of Lipid Research, 100221.
266. . Li, F., Chen, T., Wang, F., Chen, J., Zhang, Y., Song, D., ... & Zhuang, J. (2022). Enhanced Cancer Starvation Therapy Enabled by an Autophagy Inhibitors-Encapsulated Biomimetic ZIF-8 Nanodrug: Disrupting and Harnessing Dual Pro-Survival Autophagic Responses. ACS Applied Materials & Interfaces.
267. Cao, X., Shao, Y., Meng, P., Cao, Z., Yan, G., Yao, J., ... & Lu, H. (2022). Nascent Proteome and Glycoproteome Reveal the Inhibition Role of ALG1 in Hepatocellular Carcinoma Cell Migration. Phenomics, 1-12.
268. Lv, Y. Y., Wang, H., Fan, H. T., Xu, T., Xin, W. J., & Guo, R. X. (2022). SUMOylation of Kir7. 1 participates in neuropathic pain through regulating its membrane expression in spinal cord neurons. CNS Neuroscience & Therapeutics.
269. Ren, D., Li, J. N., Qiu, X. T., Wan, F. P., Wu, Z. Y., Fan, B. Y., ... & Li, Y. Q. (2022). Anterior cingulate cortex mediates hyperalgesia and anxiety induced by chronic pancreatitis in rats. Neuroscience bulletin, 38(4), 342-358.
270. Li, Weili, Haiyang Li, Lujuan Zheng, Jing Xia, Xiaoxuan Yang, Ye Yuan, and Yuying Fan. "Ginsenoside CK improves skeletal muscle insulin resistance by activating DRP1/PINK1-mediated mitophagy." (2022)
271. Liu, Y., Tian, X., Ke, P., Gu, J., Ma, Y., Guo, Y., ... & Xiao, F. (2022). KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B. Neuroscience Bulletin, 1-16.
272. Fukuyama, K., Motomura, E., & Okada, M. (2022). Brexpiprazole Reduces 5-HT7 Receptor Function on Astroglial Transmission Systems. International Journal of Molecular Sciences, 23(12), 6571.
273. Song, B. R., Alam, M. B., & Lee, S. H. (2022). Terpenoid-Rich Extract of Dillenia indica L. Bark Displays Antidiabetic Action in Insulin-Resistant C2C12 Cells and STZ-Induced Diabetic Mice by Attenuation of Oxidative Stress. Antioxidants, 11(7), 1227.
274. Sung, J. H., Ou, Y., & Barger, S. W. (2022). Amyloid β-peptide impacts on glucose regulation are dependent on apolipoprotein E genotype. bioRxiv.
275. . Dubrovsky, L., Brichacek, B., Prashant, N. M., Pushkarsky, T., Mukhamedova, N., Dragoljevic, D., ... & Bukrinsky, M. I. (2022). Extracellular vesicles carrying HIV-1 Nef induce trained immunity in myeloid cells. bioRxiv.
276. Müller, G. A., & Müller, T. D. (2022). Biological Role of the Intercellular Transfer of Glycosylphosphatidylinositol-Anchored Proteins: Stimulation of Lipid and Glycogen Synthesis. International Journal of Molecular Sciences, 23(13), 7418.
277.  Xu, W., Wang, Y., Li, L., Qu, X., Liu, Q., Li, T., ... & Li, C. (2022). Transmembrane domain of IFITM3 is responsible for its interaction with influenza virus HA2 subunit. Virologica Sinica.
278.  Han, Y., Xiong, C., Zhang, L. Z., Wang, Y. D., Yang, G., & Guo, Z. (2022). Antagonism of N/OFQ attenuates externalization of β1-adrenergic receptor and ventricular arrhythmias in acute myocardial ischemia rat model. European Journal of Pharmacology, 175139.
279. Zhong, W., Lin, W., Yang, Y., Chen, D., Cao, X., Xu, M., ... & Yan, D. (2022). An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis. Nature Communications, 13(1), 1-18.
280. Cao, R., Li, Z., Wu, C., Ji, S., Li, Y., Cao, X., ... & Zhang, C. J. (2022). Identification of a Small Molecule with Strong Anti-Inflammatory Activity in Experimental Autoimmune Encephalomyelitis and Sepsis through Blocking Gasdermin D Activation. The Journal of Immunology.
281. Zhang, W., Lei, M., Wen, Q., Zhang, D., Qin, G., Zhou, J., & Chen, L. (2022). Dopamine receptor D2 regulates GLUA1-containing AMPA receptor trafficking and central sensitization through the PI3K signaling pathway in a male rat model of chronic migraine. The Journal of Headache and Pain, 23(1), 1-17.
282. Kurosawa, T., Tega, Y., Uchida, Y., Higuchi, K., Tabata, H., Sumiyoshi, T., ... & Deguchi, Y. (2022). Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood–Brain Barrier. Pharmaceutics, 14(8), 1683.
283. Qiu, Y., Sha, L., Zhang, X., Li, G., Zhu, W., & Xu, Q. (2022). Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer’s disease risk. Frontiers in Aging Neuroscience, 14, 896522.
284. Zhang, X. L., Lei, Y., Xiao, Y. B., Cao, X. Y., Tian, X. Y., Zhu, Y. X., ... & Xie, M. X. (2022). Hen Egg Lysozyme alleviates static mechanical pain via NRF1-Parkin-TACAN signaling axis in sensory neurons. Neuroscience.
285. Wang, J., Liu, H., Yin, D., Zhou, M., Yin, L., Yang, Y., ... & Pan, X. (2022). CCR4-NOT Complex 2—A Cofactor in Host Cell for Porcine Epidemic Diarrhea Virus Infection. Genes, 13(9), 1504.
286. Li, S., Huang, Y., Li, T., Zhu, X., Li, W., Liu, K., & Liu, C. (2022). Glucocorticoids promote Na+ excretion in the renal epithelia of heart failure rats by suppressing transporter proteins involved in acute sodium loading. Journal of Cardiovascular Pharmacology, 80(3), 453-463.
287. Okada, M., Fukuyama, K., & Motomura, E. (2022). Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine. International Journal of Molecular Sciences, 23(16), 9103.
288. Lolicato, F., Saleppico, R., Griffo, A., Meyer, A., Scollo, F., Pokrandt, B., ... & Nickel, W. (2022). Cholesterol promotes clustering of PI (4, 5) P2 driving unconventional secretion of FGF2. Journal of Cell Biology, 221(11), e202106123.
289. Wang, H., Wu, T., Huang, Z., Huang, J., Geng, Z., Cui, B., ... & Wang, Y. (2022). Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation. Journal of Biological Chemistry, 102599.
290. Chai, Q., Yu, S., Zhong, Y., Lu, Z., Qiu, C., Yu, Y., ... & Liu, C. H. (2022). A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin. Science, 378(6616), eabq0132.
291. Liu, X., Wang, K., Hou, S., Jiang, Q., Ma, C., Zhao, Q., ... & Li, P. (2022). Insulin induces insulin receptor degradation in the liver through EphB4. Nature Metabolism, 1-12.

292.  Lim, K. M., Han, J. H., Lee, Y., Park, J., Dayem, A. A., Myung, S. H., ... & Kim, T. H. (2022). Rapid production method with increased yield of high‐purity extracellular vesicles obtained using extended mitochondrial targeting domain peptide. Journal of Extracellular Vesicles, 11(10), 12274.

293. Abe, E., Yamashita, A., Hirota, K., Yamaji, T., Azushima, K., Urate, S., ... & Takahashi, H. (2022). Angiotensin II type-1 receptor-associated protein interacts with transferrin receptor-1 and promotes its internalization. Scientific Reports, 12(1), 1-14.

294. Xi, J., Zeng, J., Fu, X., Zhang, L., Li, G., Li, B., ... & Zhang, M. (2022). GhROP6 GTPase promotes cell-specific GhPIN3a degradation in cotton fibers by regulating GhPIN3a localization. Journal of Experimental Botany.
295. Zheng, K., Liu, X., Li, M., Zhou, S., & Ding, C. (2022). Phthalocyanine-Based Nanoassembly with Switchable Fluorescence and Photoactivities for Tumor Imaging and Phototherapy. Analytical Chemistry.
296. Lin, X., Xu, L., Tan, H., Zhang, X., Shao, H., Yao, L., & Huang, X. (2022). The potential effects and mechanisms of Gegen Qinlian Decoction in oxaliplatin-resistant colorectal cancer based on network pharmacology. Heliyon, e11305.
297. Wang, F., Deng, Y., Yu, L., Zhou, A., Wang, J., Jia, J., ... & Lin, X. (2022). A Macrophage Membrane–Polymer Hybrid Biomimetic Nanoplatform for Therapeutic Delivery of Somatostatin Peptide to Chronic Pancreatitis. Pharmaceutics, 14(11), 2341.
298. Haberkorn, B., Oswald, S., Kehl, N., Gessner, A., Taudte, R. V., Dobert, J. P., ... & König, J. (2022). Cancer-Type Organic Anion Transporting Polypeptide 1B3 Is Localized in Lysosomes and Mediates Resistance against Kinase Inhibitors. Molecular Pharmacology, 102(6), 248-258.
299. Li, S., Huang, H., Wei, X., Ye, L., Ma, M., Ling, M., & Wu, Y. (2022). The recycling of AMPA receptors/GABAa receptors is related to neuronal excitation/inhibition imbalance and may be regulated by KIF5A.
300. Liu, J., Zhang, R., Su, T., Zhou, Q., Gao, L., He, Z., ... & Chen, W. (2022). Targeting PHB1 to inhibit castration-resistant prostate cancer progression in vitro and in vivo.
301. Xu, P., Zheng, Y., Liao, J., Hu, M., Yang, Y., Zhang, B., ... & Tong, C. (2022). AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre‐eclampsia. Cell Proliferation, e13358.
302. . He, D., Ren, H., Wang, H., Jose, P. A., Zeng, C., Xia, T., & Yang, J. Effect of D4 Dopamine Receptor on Na+-K+-ATPase Activity in Renal Proximal Tubule Cells. Cardiology Discovery, 10-1097.
303. Sumiya, K., Izumi, H., Adachi, Y., Mochizuki, S., & Sakurai, K. (2022). Binding assay of human Dectin-1 variants for DNA/β-glucan complex for active-targeting delivery of antisense DNA: Part II. Carbohydrate Research, 108731.
304. Rakotomamonjy, J., Rylaarsdam, L., Fares-Taie, L., McDermott, S., Davies, D., Yang, G., ... & Guemez-Gamboa, A. (2023). Impaired migration and premature differentiation underlie the neurological phenotype associated with PCDH12 loss of function. bioRxiv.
305. . Hai, Y., Zuo, L., Wang, M., Zhang, R., Wang, M., Ren, L., ... & Wang, J. (2023). Icariin Alleviates Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome by Improving Liver Fatty Acid Oxidation and Inhibiting Lipid Accumulation. Molecules, 28(2), 517.
306. Zhou, Z., Liang, S., Zhou, Z., Liu, J., Zhang, J., Meng, X., ... & Cai, S. (2023). TGF-β1 promotes SCD1 expression via the PI3K-Akt-mTOR-SREBP1 signaling pathway in lung fibroblasts. Respiratory Research, 24(1), 1-15.
307. Alejo, A., García-Castey, M., Guerra, M., Hernáez, B., Martín, V., Matamoros, T., & Andrés, G. (2023). African swine fever virus transmembrane protein pEP84R guides core assembly. PLoS pathogens, 19(1), e1011136.
308. Zhu, S., Li, Z., Zheng, D., Yu, Y., Xiang, J., Ma, X., ... & Ren, Q. (2023). A cancer cell membrane coated, doxorubicin and microRNA co-encapsulated nanoplatform for colorectal cancer theranostics. Molecular Therapy-Oncolytics, 28, 182-196.
309. Fukuyama, K., Motomura, E., & Okada, M. (2023). Opposing effects of clozapine and brexpiprazole on β-aminoisobutyric acid: Pathophysiology of antipsychotics-induced weight gain. Schizophrenia, 9(1), 8.
310. . Wang, X., Wen, Z., Cao, H., Luo, J., Shuai, L., Wang, C., ... & Wang, J. (2023). Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2. Journal of Virology, e01611-22.
311. . Paul, I., Bolzan, D., Youssef, A., Gagnon, K. A., Hook, H., Karemore, G., ... & Emili, A. (2023). Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT. Nature Communications, 14(1), 688.
312. Saeed, B., Deligne, F., Brillada, C., Dünser, K., Ditengou, F. A., Turek, I., ... & Trujillo, M. (2023). K63-linked ubiquitin chains are a global signal for endocytosis and contribute to selective autophagy in plants. Current Biology.
313. Wang, I. H., Usukura, J., Miyake, Y., Usukura, E., Narita, A., Endou, T., ... & Kawaoka, Y. (2023). Influenza A virus uses actomyosin for genome packaging at the cell membrane.
314. Huang, J. Q., Duan, L. X., Liu, Q. Y., Li, H. F., Hu, A. P., Song, J. W., ... & Gong, L. Y. (2023). Serine-arginine protein kinase 1 (SRPK1) promotes EGFR-TKI resistance by enhancing GSK3β Ser9 autophosphorylation independent of its kinase activity in non-small-cell lung cancer. Oncogene, 1-14.
315. Fukuyama, K., Motomura, E., & Okada, M. (2023). A Candidate Gliotransmitter, L-β-Aminoisobutyrate, Contributes to Weight Gain and Metabolic Complication Induced by Atypical Antipsychotics. Nutrients, 15(7), 1621.
316. Fiorenza, M., Onslev, J., Henríquez-Olguín, C., Jensen, T. E., Wojtaszewski, J. F., Hostrup, M., & Bangsbo, J. (2023). Reducing the mitochondrial oxidative burden alleviates lipid-induced insulin resistance in human skeletal muscle. bioRxiv, 2023-04.
317. Wang, M., Xian, P., Zheng, W., Li, Z., Chen, A., Xiao, H., ... & Wu, S. (2023). Axin2 coupled excessive Wnt‐glycolysis signaling mediates social defect in autism spectrum disorders. EMBO Molecular Medicine, e17101.
318. Huang, H. C., Wang, T. Y., Rousseau, J., Mungaray, M., Michaud, C., Plaisier, C., ... & Wang, K. C. (2023). Lesion-specific suppression of YAP/TAZ by biomimetic nanodrug ameliorates atherosclerosis development. bioRxiv, 2023-04.
319. Zhang, Y., Yuan, W., Liu, Y., Liu, Y., Liang, H., Xu, Q., ... & Weng, X. (2023). Plasma membrane lipid composition and metabolomics analysis of Yorkshire boar sperms with high and low resistance to cryopreservation. Theriogenology.
320. Gu, J., Ke, P., Guo, H., Liu, J., Liu, Y., Tian, X., ... & Xiao, F. (2023). KCTD13-mediated ubiquitination and degradation of GluN1regulates excitatory synaptic transmission and seizure susceptibility. Cell Death & Differentiation, 1-16.

321.  Chen, H., Lu, C., Tan, Y., Weber-Boyvat, M., Zheng, J., Xu, M., ... & Zhong, W. (2023). Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI (4, 5) P2 hydrolysis in the plasma membrane. Journal of Biological Chemistry, 104812.

322. Zhou, C., Liu, Y., Wei, Q., Chen, Y., Yang, S., Cheng, A., & Zhang, G. (2023). HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway. Journal of Virology, e00549-23.
323. Bogucka-Janczi, K., Harms, G., Coissieux, M. M., Bentires-Alj, M., Thiede, B., & Rajalingam, K. (2023). ERK3/MAPK6 dictates Cdc42/Rac1 activity and ARP2/3-dependent actin polymerization. Elife, 12, e85167.
324. Li, W., Shen, Z., Yin, X., Chang, W., Chen, X., Yu, J., & Xu, S. (2023). Reduction of p11 in Dorsal Raphe Nucleus Serotonergic Neurons Mediates Depression-like Behaviors.
325. Li, Y., Li, K., Pan, T., Xie, Q., Cheng, Y., Wu, X., ... & Cui, S. (2023). Translocation of IGF-1R in endoplasmic reticulum enhances SERCA2 activity to trigger Ca2+ ER perturbation in hepatocellular carcinoma. Acta Pharmaceutica Sinica B.
326. Desai, N., Rana, D., Pande, S., Salave, S., Giri, J., Benival, D., & Kommineni, N. (2023). “Bioinspired” Membrane-Coated Nanosystems in Cancer Theranostics: A Comprehensive Review. Pharmaceutics, 15(6), 1677.
327. Zhou, J., Shi, Y., Yang, C., Lu, S., Zhao, L., Liu, X., ... & Yin, Z. (2023). γ-glutamylcysteine alleviates insulin resistance and hepatic steatosis by regulating adenylate cyclase and IGF-1R/IRS1/PI3K/Akt signaling pathways. The Journal of Nutritional Biochemistry, 109404.
328. Deng, D. X., Li, C. Y., Zheng, Z. Y., Wen, B., Liao, L. D., Zhang, X. J., ... & Xu, L. Y. (2023). Prenylated PALM2 Promotes the Migration of Esophageal Squamous Cell Carcinoma Cells through Activating Ezrin. Molecular & Cellular Proteomics, 100593.
329. Zhang, J. J., Song, C. G., Wang, M., Zhang, G. Q., Wang, B., Chen, X., ... & Chen, Z. N. (2023). Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis. Journal of Pharmaceutical Analysis.
330. Gao, Y., Feng, Y., Liu, S., Zhang, Y., Wang, J., Qin, T., ... & Li, K. (2023). Immune‐independent acquired resistance to PD‐L1 antibody initiated by PD‐L1 upregulation via PI3K/AKT signaling can be reversed by anlotinib. Cancer Medicine.
331. Meng, X., ... & Cai, S. (2023). TGF-β1 promotes SCD1 expression via PI3K-Akt-mTOR-SREBP1 signaling pathway in lung fibroblasts. Respiratory Research, 24(1), 8.
332. Sorrin, A. J., Zhou, K., May, K., Liu, C., McNaughton, K., Rahman, I., ... & Huang, H. C. (2023). Transient fluid flow improves photoimmunoconjugate delivery and photoimmunotherapy efficacy. iScience.
333. Liu, N., Li, J., Gao, K., Perszyk, R. E., Zhang, J., Wang, J., ... & Jiang, Y. De novo CLPTM1 variants with reduced GABAAR current response in patients with epilepsy. Epilepsia.
334. Wang, T., Luo, R., Zhang, J., Lu, Z., Li, L. F., Zheng, Y. H., ... & Qiu, H. J. (2023). The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKK α and IKK β through the recruitment of TOLLIP. PLoS pathogens, 19(8), e1011580.
335. Zhang, J., Tang, J., Li, G., Li, N., Wang, J., Yao, R., & Yu, T. SINE-VNTR-Alu retrotransposon insertion as a novel mutational event underlying Glanzmann thrombasthenia. Journal of Thrombosis and Haemostasis.
336. Chen, Y., Li, X., Xiong, Q., Du, Y., Luo, M., Yi, L., ... & Dong, Z. (2023). Inhibiting NLRP3 inflammasome signaling pathway promotes neurological recovery following hypoxic-ischemic brain damage by increasing p97-mediated surface GluA1-containing AMPA receptors. Journal of Translational Medicine, 21(1), 1-18.
337. . Tao, Y., Luo, W., Chen, Y., Chen, C., Chen, S., Li, X., ... & Zeng, C. (2023). Exercise ameliorates skeletal muscle insulin resistance by modulating GRK4-mediated D1R expression. Clinical Science, 137(17), 1391-1407.
338. Zuo, Z., Yin, H., Zhang, Y., Xie, C., & Wang, Q. (2023). A cytotoxic T cell inspired oncolytic nanosystem promotes lytic cell death by lipid peroxidation and elicits antitumor immune responses. Nature Communications, 14(1), 5456.
     
339. Ma, Y., Han, C., Xie, C., Dang, Q., Yang, L., Li, Y., ... & Li, P. ATP promotes resident CD34+ cell migration mainly through P2Y2-Stim1-ERK/p38 pathway. American journal of physiology. Cell physiology.

340. Zhao, H., Liu, R., Wang, L., Tang, F., Chen, W., & Liu, Y. N. (2023). Artificial Macrophage with Hierarchical Nanostructure for Biomimetic Reconstruction of Antitumor Immunity. Nano-Micro Letters, 15(1), 216.

341. Wang, X., Zhou, R., Sun, X., Li, J., Wang, J., Yue, W., ... & Zhang, D. (2023). Preferential Regulation of Γ‐Secretase‐Mediated Cleavage of APP by Ganglioside GM1 Reveals a Potential Therapeutic Target for Alzheimer's Disease. Advanced Science, 2303411.

342. Thomas, M. A., Kim, S. Y., Curran, A. M., Smith, B., Antiochos, B., Na, C. H., & Darrah, E. (2023). An unbiased proteomic analysis of PAD4 in human monocytes: novel substrates, binding partners and subcellular localizations. Philosophical Transactions of the Royal Society B, 378(1890), 20220477.

343. Jiang, Q., Wang, H., Qiao, Z., Hou, Y., Sui, Z., Zhao, B., ... & Zhang, L. (2023). Metal organic layers enabled cell surface engineering coupling biomembrane fusion for dynamic membrane proteome profiling. Chemical Science.

344. Zhao, F., Hang, K., Zhou, Q., Shao, L., Li, H., Li, W., ... & Wang, M. W. (2023). Molecular basis of signal transduction mediated by the human GIPR splice variants. Proceedings of the National Academy of Sciences, 120(41), e2306145120.

345. Li, S., Wei, X., Huang, H., Ye, L., Ma, M., Sun, L., ... & Wu, Y. (2023). Neuroplastin exerts antiepileptic effects through binding to the α1 subunit of GABA type A receptors to inhibit the internalization of the receptors. Journal of Translational Medicine, 21(1), 1-16.

346. Kawakami, F., Imai, M., Isaka, Y., Cookson, M. R., Maruyama, H., Kubo, M., ... & Ichikawa, T. LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes. FEBS Open Bio.

347. Takahashi, M., Araki, T., Yashima, H., Nagamine, A., Nagano, D., & Yamamoto, K. (2023). Increased c‑SRC expression is involved in acquired resistance to lenvatinib in hepatocellular carcinoma. Oncology Letters, 26(6), 1-7.

348. Yu, L., Xu, M., Yan, Y., Huang, S., Yuan, M., Cui, B., ... & Wang, Y. (2023). ZFYVE28 mediates insulin resistance by promoting phosphorylated insulin receptor degradation via increasing late endosomes production. Nature Communications, 14(1), 6833.

349. Luo, M., Pang, Y., Li, J., Yi, L., Wu, B., Tian, Q., ... & Dong, Z. (2023). miR-429-3p mediates memory decline by targeting MKP-1 to reduce surface GluA1-containing AMPA receptors in a mouse model of Alzheimer’s disease. Acta Pharmaceutica Sinica B.

350. Wang, C., Zhao, X., Zhao, L., Wang, Y., Jia, Y., Zhang, X., & Ma, W. (2023). PKCζ phosphorylates VASP to mediate chemotaxis in breast cancer cells. Experimental Cell Research, 113823.

351. Jiang, R., Li, L., Wang, B., Liu, L., Liu, L., Xian, X., & Li, W. B. (2023). Ceftriaxone modulates ubiquitination of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors to improve long-term potentiation impairment induced by exogenous β-amyloid in a glutamate transporter-1 dependent manner.

352. Ma, J., Xie, W., Wang, J., Tian, S., Zhao, H., Liang, Z., ... & Jiang, F. (2023). RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis.

353. Zhang, Q., Weng, W., Gu, X., Xiang, J., Yang, Y., Zhu, M. X., ... & Li, Y. (2023). hnRNPA1 SUMOylation promotes cold hypersensitivity in chronic inflammatory pain by stabilizing TRPA1 mRNA. Cell Reports, 42(11).

354. Lo, H. C., Hua, W. J., Yeh, H., Lin, Z. H., Huang, L. C., Ciou, Y. R., ... & Lin, T. Y. (2023). GMI, a Ganoderma microsporum protein, abolishes focal adhesion network to reduce cell migration and metastasis of lung cancer. Life Sciences, 122255.

355. Wang, H., Yu, L., Wang, J. E., Zhang, Y., Xu, M., Lv, C., ... & Wang, Y. (2023). SLC35D3 promotes white adipose tissue browning to ameliorate obesity by NOTCH signaling. Nature Communications, 14(1), 7643.

356. Ma, H., Huo, J., Xin, C., Yang, J., Liu, Q., Dong, H., ... & Liu, Y. (2023). RABGGTB plays a critical role in ALS pathogenesis. Brain Research Bulletin, 110833.

357. Perumal, N., Yurugi, H., Dahm, K., Rajalingam, K., Grus, F. H., Pfeiffer, N., & Manicam, C. (2023). Proteome landscape and interactome of voltage-gated potassium channel 1.6 (Kv1. 6) of the murine ophthalmic artery and neuroretina. International Journal of Biological Macromolecules, 128464.

358. Yu, D. M., Zhao, J., Lee, E. E., Kim, D., Mahapatra, R., Rose, E. K., ... & Wang, R. C. (2023). GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing. The Journal of clinical investigation, 133(21).

359. Fohmann, I., Weinmann, A., Schumacher, F., Peters, S., Prell, A., Weigel, C., ... & Schubert-Unkmeir, A. (2023). Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells. PLoS pathogens, 19(11), e1011842.

360. Day, R. B., Hickman, J. A., Xu, Z., Katerndahl, C. D., Ferraro, F., Ramakrishnan, S. M., ... & Ley, T. J. (2023). Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia-initiating CBFB:: MYH11 oncofusion protein. The Journal of Clinical Investigation.

361. Fujii, T., Nakano, Y., Hagita, D., Onishi, N., Endo, A., Nakagawa, M., ... & Tomiyama, A. (2023). KLC1-ROS1 Fusion Exerts Oncogenic Properties of Glioma Cells via Specific Activation of JAK-STAT Pathway. Cancers, 16(1), 9.

362. Sanchez-Guerrero, G., Umbaugh, D. S., Ramachandran, A. A., Artigues, A., Jaeschke, H., & Ramachandran, A. (2023). Translocation of Adenosine A2B Receptor to Mitochondria Influences Cytochrome P450 2E1 Activity after Acetaminophen Overdose. Livers, 4(1), 15-30.

363. Yu, L., Zhou, A., Jia, J., Wang, J., Ji, X., Deng, Y., ... & Wang, F. (2023). Immunoactivity of a hybrid membrane biosurface on nanoparticles: enhancing interaction with dendritic cells to augment anti-tumor immune responses. Biomaterials Science.

364. Yu, L., Liu, X., Wei, X., Ren, J., Wang, X., Wu, S., & Lan, K. (2024). C1QTNF5 is a novel attachment factor that facilitates the entry of influenza A virus. Virologica Sinica.

365. Matsumura, K., Mori, T., Dohi, T., Kawamura, Y. I., & Takaki, S. (2024). Composition of fatty acids in a high‐fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells. European Journal of Immunology, 2350800.

366. Fukuyama, K., Motomura, E., & Okada, M. (2024). Age-Dependent Activation of Pannexin1 Function Contributes to the Development of Epileptogenesis in Autosomal Dominant Sleep-related Hypermotor Epilepsy Model Rats. International Journal of Molecular Sciences, 25(3), 1619.

367. Wang, H., Ni, X., Clark, N., Randall, K., Boeglin, L., Chivukula, S., ... & Sun, G. (2024). Absolute quantitation of human wild-type DNAI1 protein in lung tissue using a nanoLC-PRM-MS-based targeted proteomics approach coupled with immunoprecipitation. Clinical Proteomics, 21(1), 1-9.

368. Liu, C., Jiao, B., Wang, P., Zhang, B., Gao, J., Li, D., ... & Ren, R. (2024). GOLGA7 is essential for NRAS trafficking from the Golgi to the plasma membrane but not for its palmitoylation. Cell Communication and Signaling, 22(1), 98.

369. Fukuyama, K., Motomura, E., & Okada, M. (2024). Age-Dependent Activation of Purinergic Transmission Contributes to the Development of Epileptogenesis in ADSHE Model Rats. Biomolecules, 14(2), 204.

370. Dodantenna, N., Cha, J. W., Chathuranga, K., Chathuranga, W. A., Weerawardhana, A., Ranathunga, L., ... & Lee, J. S. (2024). The African Swine Fever Virus Virulence Determinant DP96R Suppresses Type I IFN Production Targeting IRF3. International Journal of Molecular Sciences, 25(4), 2099.
     

371. Wang, H., Li, Q., Yuan, Y. C., Han, X. C., Cao, Y. T., & Yang, J. K. (2024). KCNH6 channel promotes insulin exocytosis via interaction with Munc18-1 independent of electrophysiological processes. Cellular and Molecular Life Sciences, 81(1), 1-18.

372.  Huang, H. C., Wang, T. Y., Rousseau, J., Orlando, M., Mungaray, M., Michaud, C., ... & Wang, K. C. (2024). Biomimetic nanodrug targets inflammation and suppresses YAP/TAZ to ameliorate atherosclerosis. Biomaterials, 122505.

373. Xiong, F. R., Lu, J., Zhu, J. J., Zhao, R. X., Zhang, Y. C., & Yang, J. K. (2024). KCNH6 is essential for insulin secretion by regulating intracellular ER Ca2+ store. The FASEB Journal, 38(4), e23490.

374. Liu, W., Zhang, X., Sunakawa, H., Perera, L. M. B., Martha, L., Mizoi, K., & Ogihara, T. (2024). Mechanism of Induction of P-gp Activity During MET Induced by DEX in Lung Cancer Cell Line. Journal of Pharmaceutical Sciences.

375. Mooney, B., Negri, G. L., Shyp, T., Delaidelli, A., Zhang, H. F., Spencer Miko, S. E., ... & Sorensen, P. H. (2024). Surface and global proteome analyses identify ENPP1 and other surface proteins as actionable immunotherapeutic targets in Ewing sarcoma. Clinical Cancer Research, 30(5), 1022-1037.(Mass)

376. Zheng, H., An, M., Luo, Y., Diao, X., Zhong, W., Pang, M., ... & Lin, T. (2024). PDGFRα+ ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay. Cancer Cell.

377. Dong, Y., Wang, J., Yang, C., Bao, J., Liu, X., Chen, H., ... & Zhang, G. (2024). Phosphorylated CPI-17 and MLC2 as Biomarkers of Coronary Artery Spasm–Induced Sudden Cardiac Death. International Journal of Molecular Sciences, 25(5), 2941.

378. Xie, M. X., Lai, R. C., Xiao, Y. B., Zhang, X., Cao, X. Y., Tian, X. Y., ... & Zhang, X. L. (2024). Endophilin A2 controls touch and mechanical allodynia via kinesin-mediated Piezo2 trafficking. Military Medical Research, 11(1), 17.

379. Schempp, R., Eilts, J., Schöl, M., Grijalva Yépez, M. F., Fekete, A., Wigger, D., ... & Avota, E. (2024). The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells. International Journal of Molecular Sciences, 25(6), 3247.

380. Wang, T., Luo, R., Zhang, J., Lan, J., Lu, Z., Zhai, H., ... & Qiu, H. J. (2024). The African swine fever virus MGF300-4L protein is associated with viral pathogenicity by promoting the autophagic degradation of IKKβ and increasing the stability of IκBα. Emerging Microbes & Infections, (just-accepted), 2333381.

381. Liu, L., Chen, X., Wu, L., Huang, K., Wang, Z., Zheng, Y., ... & Xu, Y. (2024). Ubiquitin ligase subunit FBXO9 inhibits V-ATPase assembly and impedes lung cancer metastasis. Experimental Hematology & Oncology, 13(1), 1-23.

382. Meng, J. H., Huang, Y. B., Long, J., Cai, Q. C., Qiao, X., Zhang, Q. L., ... & Luo, K. J. (2024). Innexin hemichannel activation by Microplitis bicoloratus ecSOD monopolymer reduces ROS. iScience.

383. Wang, Y., Li, N., Liang, G., Wang, L., Zhang, X., Cui, Z., ... & Zhang, L. (2024). Identification of host protein ENO1 (alpha-enolase) interacting with Cryptosporidium parvum sporozoite surface protein, Cpgp40. Parasites & Vectors, 17(1), 1-13.

384. Čaval, T., Xu, G., Baniasad, M., Chu, C. W., Rice, R., Hundal, I., ... & Schwarz, F. (2024). Mass Spectrometry Analysis of Glycopeptides Enriched by Anion Exchange-Mediated Methods Reveals PolyLacNAc-Extended N-Glycans in Integrins and Tetraspanins in Melanoma Cells. Analytical Chemistry.

385. .  Jia, R., Zhu, G., Zhao, R., Li, T., Jiang, W., & Cui, X. (2024). Hydrogen treatment reduces electroencephalographic activity and neuronal death in rats with refractory status epilepticus by inhibiting membrane NR2B phosphorylation and oxidative stress. Journal of International Medical Research, 52(3), 03000605241235589.

386. Ye, F., Yuan, Z., Tang, Y., Li, J., Liu, X., Sun, X., ... & Zhou, H. (2024). Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion. Cell Reports, 43(4).

387.  Jiang, Y. L., Xia, L., Zhao, J. J., Zhou, H. M., Mi, D., Wang, X., ... & Jiang, W. (2024). Mice harboring the T316N variant in the GABAAR γ2 subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway. Experimental Neurology, 114775.

388. Li, Q., Xia, Z., Wu, Y., Ma, Y., Zhang, D., Wang, S., ... & Xue, M. (2024). Lysophospholipid acyltransferase‐mediated formation of saturated glycerophospholipids maintained cell membrane integrity for hypoxic adaptation. The FEBS Journal.

389. Zheng, J., Wu, J., Xie, L., Huang, Y., Hong, J., & Chen, C. (2024). Paclitaxel aggravating radiation-induced pulmonary fibrosis is associated with the down-regulation of the negative regulatory function of Spry2. Journal of Pharmacology and Experimental Therapeutics, 389(2), 197-207.

390. Wang, H., Wang, J., Cui, H., Fan, C., Xue, Y., Liu, H., ... & Xu, M. (2024). Inhibition of fatty acid uptake by TGR5 prevents diabetic cardiomyopathy. Nature Metabolism, 1-17.

391. Eschrig, S., Schäffer, M., Shu, L. J., Illig, T., Eibel, S., Fernandez, A., & Ranf, S. (2024). LORE receptor homomerization is required for 3‐hydroxydecanoic acid‐induced immune signaling and determines the natural variation of immunosensitivity within the Arabidopsis genus. New Phytologist.

392. Ramsay, E., Montaser, A. B., Niitsu, K., Urtti, A., Auriola, S., Huttunen, K. M., ... & Terasaki, T. (2024). Transporter Protein Expression of Corneal Epithelium in Rabbit and Porcine: Evaluation of Models for Ocular Drug Transport Study. Molecular Pharmaceutics

393. Li, X., Kirkpatrick, R. B., Wang, X., Tucker, C. J., Shukla, A., Jessen, H. J., ... & Gu, C. (2024). Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8. Cell Reports, 43(6).

394. Ni, Z., Wang, J., Yu, X., Wang, Y., Wang, J., He, X., ... & Bu, Z. (2024). Influenza virus uses mGluR2 as an endocytic receptor to enter cells. Nature Microbiology, 1-14.

395. Wang, S., Yu, L., Guo, H., Zuo, W., Guo, Y., Liu, H., ... & Wang, M. (2024). Gastrodin Ameliorates Post-Stroke Depressive-Like Behaviors Through Cannabinoid-1 Receptor-Dependent PKA/RhoA Signaling Pathway. Molecular Neurobiology, 1-20.

396. Guo, L., Zong, Y., Yang, W., Lin, Y., Feng, Q., Yu, C., ... & Nie, L. (2024). DCBLD2 deletion increases hyperglycemia and induces vascular remodeling by inhibiting insulin receptor recycling in endothelial cells. The FEBS Journal.

397. Li, Y., Wang, X., Bi, Y., Zhang, M., Xiong, W., Hu, X., ... & He, F. (2024). SNX5-Rab11a protects against cardiac hypertrophy through regulating LRP6 membrane translocation. Journal of Molecular and Cellular Cardiology.

398. Sun, J. T., Wang, Z. M., Zhou, L. H., Yang, T. T., Zhao, D., Bao, Y. L., ... & Wang, L. S. (2024). PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3. Communications Biology, 7(1), 795.

399. Schöl, M., Schempp, R., Hennig, T., Wigger, D., Schumacher, F., Kleuser, B., ... & Avota, E. (2024). Dynamic changes in the proximitome of neutral sphingomyelinase-2 (nSMase2) in TNFα stimulated Jurkat cells. Frontiers in Immunology, 15, 1435701.

400. Liang, J., Wan, Y., Gao, J., Zheng, L., Wang, J., Wu, P., ... & Shi, L. (2024). Erythroid-intrinsic activation of TLR8 impairs erythropoiesis in inherited anemia. Nature Communications, 15(1), 5678.

401. Vanpouille, C., Brichacek, B., Pushkarsky, T., Dubrovsky, L., Fitzgerald, W., Mukhamedova, N., ... & Bukrinsky, M. (2024). HIV‐1 Nef is carried on the surface of extracellular vesicles. Journal of Extracellular Vesicles, 13(7).
402. Fan, Y. G., Ge, R. L., Ren, H., Jia, R. J., Wu, T. Y., Lei, X. F., ... & Wang, Z. Astrocyte-Derived Lactoferrin Inhibits Neuronal Ferroptosis by Reducing Iron Content and Gpx4 Degradation in App/Ps1 Transgenic Mice. 
403. Cheng, X., Zhao, M., Chen, L., Huang, C., Xu, Q., Shao, J., ... & Xiong, Z. Q. (2024). Astrocytes modulate brain phosphate homeostasis via polarized distribution of phosphate uptake transporter PiT2 and exporter XPR1. Neuron.

404. Hatano, E., Akhter, N., Anada, R., Ono, M., Oohashi, T., Kuboki, T., ... & Hara, E. S. (2024). The cell membrane as biofunctional material for accelerated bone repair. Acta Biomaterialia.

405. Okada, M., Fukuyama, K., & Motomura, E. (2024). Impacts of exposure to and subsequent discontinuation of clozapine on tripartite synaptic transmission. British Journal of Pharmacology.
406. Arizanovska, D., Dallera, C. A., Folorunso, O. O., Bush III, G. F., Frye, J. B., Doyle, K. P., ... & Liebl, D. J. (2024). Cognitive dysfunction following brain trauma results from sex-specific reactivation of the developmental pruning processes. bioRxiv, 2024-08.

407. Weng, C., Xu, J., Ying, X., Sun, S., Hu, Y., Wang, X., ... & Li, M. (2024). The PDIA3-STAT3 protein complex regulates IBS formation and development via CTSS/MHC-II pathway-mediated intestinal inflammation. Heliyon, e36357.

408. Zhang, Z., Xing, J., Tang, X., Sheng, X., Chi, H., & Zhan, W. (2024). Nectin1 is a pivotal host factor involved in attachment and entry of red-spotted grouper nervous necrosis virus in the early stages of the viral life cycle. Journal of Virology, e00901-24.

409. Zhang, X., Sun, S., Zhao, W., Wang, L., Liang, G., Wang, Y., ... & Zhang, S. (2024). A single-pass type I membrane protein, mannose-specific L-type lectin, potentially involved in the adhesion and invasion of Cryptosporidium parvum. Parasite, 31, 51. 
410. Midorikawa, R., Wakazono, Y., & Takamiya, K. (2024). Aβ peptide enhances GluA1 internalization via lipid rafts in Alzheimer's-related hippocampal LTP dysfunction. Journal of Cell Science, 137(8), jcs261281.
411. Wu, S., Liu, H., Liu, X., Wang, Y., Song, X., & Hu, K. (2024). Ginsenoside Rb1-loaded bionic nanoparticles alleviate sepsis-induced acute lung injury by reducing mitochondrial oxidative stress to inhibit macrophage PANoptosis. Materials & Design, 113291.
412. Ren, L., Wan, J., Li, X., Yao, J., Ma, Y., Meng, F., ... & Wang, H. (2024). Mitochondrial rewiring with small-molecule drug-free nanoassemblies unleashes anticancer immunity. Nature Communications, 15(1), 1-20.
413. Malamos, P., Kalyvianaki, K., Panagiotopoulos, A. A., Vogiatzoglou, A. P., Tsikalaki, A. A., Katifori, A., ... & Kampa, M. (2024). Nuclear translocation of the membrane oxoeicosanoid/androgen receptor, OXER1: possible mechanisms involved. Molecular and Cellular Endocrinology, 112357.

414.  Qiu, F., Xie, D., Chen, H., Wang, Z., Huang, J., Cao, C., ... & Liang, C. (2024). Generation of cytotoxic aptamers specifically targeting fibroblast-like synoviocytes by CSCT-SELEX for treatment of rheumatoid arthritis. Annals of the Rheumatic Diseases.

415. Zhu, X., Huang, Y., Qiu, J., Zhong, Z., Peng, Y., Liang, X., ... & Ding, Y. (2024). Chaihu Guizhi Decoction Prevents Cognitive, Memory Impairments and Sensorimotor Gating Deficit Induced by N-methyl-d-aspartate Receptor Antibody in Mice. Journal of Ethnopharmacology, 118806.